FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023150273> ?p ?o ?g. }

• W2023150273 endingPage "1247" @default.
• W2023150273 startingPage "1238" @default.
• W2023150273 abstract "PURPOSE: The majority of patients with epithelial ovarian cancer (EOC) who achieve a complete remission with front-line chemotherapy develop recurrent disease. Carboplatin and paclitaxel are used for patients with platinum-sensitive recurrent disease, although there is little information regarding the response and survival in unselected patients treated with this strategy. We sought to determine the outcomes for patients with EOC treated with carboplatin and paclitaxel at the time of first recurrence. In addition, we sought to define a new paradigm for disease transition in patients with EOC. PATIENTS AND METHODS: Eighty-nine patients were identified who had a complete response to front-line platinum-based chemotherapy for EOC, relapsed 6 months after completion of front-line chemotherapy, and were treated with carboplatin and paclitaxel as second-line therapy. RESULTS: Eighty-four cases were available for analysis of survival end points, and 66 were assessable for response. The median follow-up was 27 months. The overall response rate was 70%. The median progression-free interval for the cohort was 13 months (95% confidence interval [CI], 10.7 to 13.8 months). The 3-year survival rate was 72% (95% CI, 59.4 to 86.1%). Toxicity was limited, and no deaths from treatment were observed. Using this data, it is possible to construct a disease states model of EOC, which provides risk estimates for transitions between clinically distinct categories. CONCLUSION: Re-treatment with carboplatin and paclitaxel is effective as initial therapy in recurrent EOC. This should form the basis of a randomized trial to determine the best agents for initial treatment of relapse from EOC in potentially platinum-sensitive patients." @default.
• W2023150273 created "2016-06-24" @default.
• W2023150273 creator A5012175652 @default.
• W2023150273 creator A5032196793 @default.
• W2023150273 creator A5034670220 @default.
• W2023150273 creator A5035446911 @default.
• W2023150273 creator A5040266917 @default.
• W2023150273 creator A5054602117 @default.
• W2023150273 creator A5073323475 @default.
• W2023150273 creator A5090740287 @default.
• W2023150273 date "2002-03-01" @default.
• W2023150273 modified "2023-09-27" @default.
• W2023150273 title "Retrospective Analysis of Carboplatin and Paclitaxel as Initial Second-Line Therapy for Recurrent Epithelial Ovarian Carcinoma: Application Toward a Dynamic Disease State Model of Ovarian Cancer" @default.
• W2023150273 cites W1019821529 @default.
• W2023150273 cites W1543697093 @default.
• W2023150273 cites W1854574445 @default.
• W2023150273 cites W1910585037 @default.
• W2023150273 cites W1942713680 @default.
• W2023150273 cites W1960327677 @default.
• W2023150273 cites W1981534406 @default.
• W2023150273 cites W1987437069 @default.
• W2023150273 cites W1988643240 @default.
• W2023150273 cites W2016179096 @default.
• W2023150273 cites W2063953472 @default.
• W2023150273 cites W2069885515 @default.
• W2023150273 cites W2071943265 @default.
• W2023150273 cites W2112711252 @default.
• W2023150273 cites W2117729836 @default.
• W2023150273 cites W2118370975 @default.
• W2023150273 cites W2119638404 @default.
• W2023150273 cites W2121962205 @default.
• W2023150273 cites W2138178697 @default.
• W2023150273 cites W2141258764 @default.
• W2023150273 cites W2154737435 @default.
• W2023150273 cites W2155126523 @default.
• W2023150273 cites W2245111413 @default.
• W2023150273 cites W2264872126 @default.
• W2023150273 cites W2322807983 @default.
• W2023150273 cites W2328421677 @default.
• W2023150273 cites W2403538350 @default.
• W2023150273 cites W3028515504 @default.
• W2023150273 doi "https://doi.org/10.1200/jco.20.5.1238" @default.
• W2023150273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11870166" @default.
• W2023150273 hasPublicationYear "2002" @default.
• W2023150273 type Work @default.
• W2023150273 sameAs 2023150273 @default.
• W2023150273 citedByCount "69" @default.
• W2023150273 countsByYear W20231502732012 @default.
• W2023150273 countsByYear W20231502732013 @default.
• W2023150273 countsByYear W20231502732014 @default.
• W2023150273 countsByYear W20231502732016 @default.
• W2023150273 countsByYear W20231502732017 @default.
• W2023150273 countsByYear W20231502732018 @default.
• W2023150273 countsByYear W20231502732020 @default.
• W2023150273 countsByYear W20231502732021 @default.
• W2023150273 crossrefType "journal-article" @default.
• W2023150273 hasAuthorship W2023150273A5012175652 @default.
• W2023150273 hasAuthorship W2023150273A5032196793 @default.
• W2023150273 hasAuthorship W2023150273A5034670220 @default.
• W2023150273 hasAuthorship W2023150273A5035446911 @default.
• W2023150273 hasAuthorship W2023150273A5040266917 @default.
• W2023150273 hasAuthorship W2023150273A5054602117 @default.
• W2023150273 hasAuthorship W2023150273A5073323475 @default.
• W2023150273 hasAuthorship W2023150273A5090740287 @default.
• W2023150273 hasConcept C121608353 @default.
• W2023150273 hasConcept C126322002 @default.
• W2023150273 hasConcept C141071460 @default.
• W2023150273 hasConcept C143998085 @default.
• W2023150273 hasConcept C2776694085 @default.
• W2023150273 hasConcept C2777292972 @default.
• W2023150273 hasConcept C2778239845 @default.
• W2023150273 hasConcept C2780427987 @default.
• W2023150273 hasConcept C2781451048 @default.
• W2023150273 hasConcept C2908611588 @default.
• W2023150273 hasConcept C2992773878 @default.
• W2023150273 hasConcept C71924100 @default.
• W2023150273 hasConceptScore W2023150273C121608353 @default.
• W2023150273 hasConceptScore W2023150273C126322002 @default.
• W2023150273 hasConceptScore W2023150273C141071460 @default.
• W2023150273 hasConceptScore W2023150273C143998085 @default.
• W2023150273 hasConceptScore W2023150273C2776694085 @default.
• W2023150273 hasConceptScore W2023150273C2777292972 @default.
• W2023150273 hasConceptScore W2023150273C2778239845 @default.
• W2023150273 hasConceptScore W2023150273C2780427987 @default.
• W2023150273 hasConceptScore W2023150273C2781451048 @default.
• W2023150273 hasConceptScore W2023150273C2908611588 @default.
• W2023150273 hasConceptScore W2023150273C2992773878 @default.
• W2023150273 hasConceptScore W2023150273C71924100 @default.
• W2023150273 hasIssue "5" @default.
• W2023150273 hasLocation W20231502731 @default.
• W2023150273 hasOpenAccess W2023150273 @default.
• W2023150273 hasPrimaryLocation W20231502731 @default.
• W2023150273 hasRelatedWork W1967715255 @default.
• W2023150273 hasRelatedWork W2023150273 @default.
• W2023150273 hasRelatedWork W2072767112 @default.
• W2023150273 hasRelatedWork W2105623825 @default.
• W2023150273 hasRelatedWork W2157919202 @default.
• W2023150273 hasRelatedWork W2311734504 @default.

• next