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• W2023155808 abstract "Abstract Data on the interaction between methicillin-resistant Staphylococcus aureus (MRSA) colonization and clinical infection are limited. During 2007–2008, we enrolled HIV-infected adults in Atlanta, Georgia, USA, in a prospective cohort study. Nares and groin swab specimens were cultured for S. aureus at enrollment and after 6 and 12 months. MRSA colonization was detected in 13%–15% of HIV-infected participants (n = 600, 98% male) at baseline, 6 months, and 12 months. MRSA colonization was detected in the nares only (41%), groin only (21%), and at both sites (38%). Over a median of 2.1 years of follow-up, 29 MRSA clinical infections occurred in 25 participants. In multivariate analysis, MRSA clinical infection was significantly associated with MRSA colonization of the groin (adjusted risk ratio 4.8) and a history of MRSA infection (adjusted risk ratio 3.1). MRSA prevention strategies that can effectively prevent or eliminate groin colonization are likely necessary to reduce clinical infections in this population." @default.
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• W2023155808 date "2013-04-01" @default.
• W2023155808 modified "2023-09-27" @default.
• W2023155808 title "Methicillin-Resistant<i>Staphylococcus aureus</i>Colonization of the Groin and Risk for Clinical Infection among HIV-infected Adults" @default.
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• W2023155808 doi "https://doi.org/10.3201/eid1904.121353" @default.
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