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- W2023159056 abstract "A general theory of helix–coil transition of irreversibly complexed nucleoproteins is presented. The equations are tested by experimental results in basic polypeptide–DNA complexes, nucleohistone I and pea bud nucleohistones. They show good agreement between theory and experiments. The theory provides direct measurement of a fraction of DNA base pairs covered by proteins, yielding a value of about 75% histone-covered base pairs in pea bud nucleohistone. It also provides a measurement of an average number of amino acid residues per nucleotide in protein-bound regions. This number varies from 1.0 to 1.4 in DNA–polylysine or DNA–polyarginine and from 2.9 to 3.3 in nucleohistone Ia, Ib, f1, and pea bud nucleohistone." @default.
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- W2023159056 date "1973-02-01" @default.
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- W2023159056 title "Helix-coil transition in nucleoprotein?theory and applications" @default.
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- W2023159056 doi "https://doi.org/10.1002/bip.1973.360120207" @default.
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