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• W2023165863 abstract "The development of autoantibodies to different tissue-specific antigens in patients without existing history of autoimmune diseases suggests that autoimmunity may develop de novo after organ transplantation. In addition to allo-specific immune responses, tissue-specific autoimmunity also appears contribute to the host anti-graft response, and thus may affect long-term graft function. As graft failure caused by chronic rejection is a major challenge in clinical transplantation, understanding de novo autoreactivity after transplantation has important ramifications. This review investigates this emerging concept by discussing target antigens and possible pathways." @default.
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• W2023165863 date "2008-07-01" @default.
• W2023165863 modified "2023-09-26" @default.
• W2023165863 title "De novo autoimmunity after organ transplantation: Targets and possible pathways" @default.
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• W2023165863 doi "https://doi.org/10.1016/j.humimm.2008.05.003" @default.
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