FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023176599> ?p ?o ?g. }

• W2023176599 endingPage "89" @default.
• W2023176599 startingPage "84" @default.
• W2023176599 abstract "The effect of exogenous octadeccadienoic acid hydroperoxide (HPODE) on the functional properties of inner membrane of isolated rat liver mitochondria, as evaluated by the measurement of the membrane potential (Δψ) has been studied. Very low concentrations of HPODE (1.5–4.5 nmol/mg prot.) do not modify the Δψ of control mitochondria appreciably while bringing about the drop of Δψ, in a concentration-dependent mode, in mitochondria with a GSH level diminished by approx. 60%. Mitochondrial GSH depletion was obtained by intraperitoneal administration of buthionine sulfoximine, a specific inhibitor of GSH synthesis, to rats. The presence in the incubation system of GSH-methyl ester which normalizes mitochondrial GSH, fully prevents any drop in levels of Δψ induced by HPODE. The same protective effect has been presented by EGTA, which chelates the available Ca2+. Neither an antioxidant nor a specific inhibitor of mitochondrial phospholipase Ab2 are able to prevent the HPODE effect. From the results obtained we can assume that HPODE itself, at the concentrations used here, induces permeability changes in the inner membrane, with the loss of coupled functions, when the GSH mitochondrial level is below a critical value." @default.
• W2023176599 created "2016-06-24" @default.
• W2023176599 creator A5002970946 @default.
• W2023176599 creator A5008847384 @default.
• W2023176599 creator A5032342022 @default.
• W2023176599 creator A5041890483 @default.
• W2023176599 creator A5061319466 @default.
• W2023176599 date "1992-07-01" @default.
• W2023176599 modified "2023-09-23" @default.
• W2023176599 title "Mitochondrial inner membrane permeability changes induced by octadecadienoic acid hydroperoxide. Role of mitochondrial GSH pool" @default.
• W2023176599 cites W1495757056 @default.
• W2023176599 cites W1535828429 @default.
• W2023176599 cites W1543177856 @default.
• W2023176599 cites W1555283812 @default.
• W2023176599 cites W1578501502 @default.
• W2023176599 cites W1699447737 @default.
• W2023176599 cites W1767614014 @default.
• W2023176599 cites W1967268953 @default.
• W2023176599 cites W1967382554 @default.
• W2023176599 cites W1970749702 @default.
• W2023176599 cites W1970820287 @default.
• W2023176599 cites W1974794685 @default.
• W2023176599 cites W1978669254 @default.
• W2023176599 cites W1987093267 @default.
• W2023176599 cites W1989264681 @default.
• W2023176599 cites W1992636509 @default.
• W2023176599 cites W1996594703 @default.
• W2023176599 cites W1999917367 @default.
• W2023176599 cites W2006525087 @default.
• W2023176599 cites W2006540841 @default.
• W2023176599 cites W2008129113 @default.
• W2023176599 cites W2012276919 @default.
• W2023176599 cites W2022371585 @default.
• W2023176599 cites W2024006352 @default.
• W2023176599 cites W2041306672 @default.
• W2023176599 cites W2045737719 @default.
• W2023176599 cites W2052406949 @default.
• W2023176599 cites W2059455970 @default.
• W2023176599 cites W2063076642 @default.
• W2023176599 cites W2073124250 @default.
• W2023176599 cites W2092037487 @default.
• W2023176599 cites W2132826785 @default.
• W2023176599 cites W2159287784 @default.
• W2023176599 cites W4238201103 @default.
• W2023176599 cites W786125826 @default.
• W2023176599 cites W87309740 @default.
• W2023176599 doi "https://doi.org/10.1016/0167-4838(92)90471-o" @default.
• W2023176599 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1633179" @default.
• W2023176599 hasPublicationYear "1992" @default.
• W2023176599 type Work @default.
• W2023176599 sameAs 2023176599 @default.
• W2023176599 citedByCount "19" @default.
• W2023176599 countsByYear W20231765992012 @default.
• W2023176599 countsByYear W20231765992022 @default.
• W2023176599 crossrefType "journal-article" @default.
• W2023176599 hasAuthorship W2023176599A5002970946 @default.
• W2023176599 hasAuthorship W2023176599A5008847384 @default.
• W2023176599 hasAuthorship W2023176599A5032342022 @default.
• W2023176599 hasAuthorship W2023176599A5041890483 @default.
• W2023176599 hasAuthorship W2023176599A5061319466 @default.
• W2023176599 hasConcept C12554922 @default.
• W2023176599 hasConcept C13591479 @default.
• W2023176599 hasConcept C178790620 @default.
• W2023176599 hasConcept C181199279 @default.
• W2023176599 hasConcept C181911157 @default.
• W2023176599 hasConcept C185592680 @default.
• W2023176599 hasConcept C190283241 @default.
• W2023176599 hasConcept C2777658833 @default.
• W2023176599 hasConcept C2778004101 @default.
• W2023176599 hasConcept C28859421 @default.
• W2023176599 hasConcept C2992270614 @default.
• W2023176599 hasConcept C31573885 @default.
• W2023176599 hasConcept C41625074 @default.
• W2023176599 hasConcept C519063684 @default.
• W2023176599 hasConcept C538909803 @default.
• W2023176599 hasConcept C55493867 @default.
• W2023176599 hasConcept C65871279 @default.
• W2023176599 hasConcept C75385678 @default.
• W2023176599 hasConcept C86803240 @default.
• W2023176599 hasConceptScore W2023176599C12554922 @default.
• W2023176599 hasConceptScore W2023176599C13591479 @default.
• W2023176599 hasConceptScore W2023176599C178790620 @default.
• W2023176599 hasConceptScore W2023176599C181199279 @default.
• W2023176599 hasConceptScore W2023176599C181911157 @default.
• W2023176599 hasConceptScore W2023176599C185592680 @default.
• W2023176599 hasConceptScore W2023176599C190283241 @default.
• W2023176599 hasConceptScore W2023176599C2777658833 @default.
• W2023176599 hasConceptScore W2023176599C2778004101 @default.
• W2023176599 hasConceptScore W2023176599C28859421 @default.
• W2023176599 hasConceptScore W2023176599C2992270614 @default.
• W2023176599 hasConceptScore W2023176599C31573885 @default.
• W2023176599 hasConceptScore W2023176599C41625074 @default.
• W2023176599 hasConceptScore W2023176599C519063684 @default.
• W2023176599 hasConceptScore W2023176599C538909803 @default.
• W2023176599 hasConceptScore W2023176599C55493867 @default.
• W2023176599 hasConceptScore W2023176599C65871279 @default.
• W2023176599 hasConceptScore W2023176599C75385678 @default.
• W2023176599 hasConceptScore W2023176599C86803240 @default.

• next