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- W2023178859 abstract "It has become increasingly apparent that eukaryotic cells possess machinery that modifies chromatin structure and that this machinery contributes to the regulation of gene expression. Identification of factors that alter chromatin structure has made possible biochemical analyses that have begun to define what structural changes each factor can cause as well as what consequences these changes have on transcription factor function. Here, a protocol that has facilitated study of energy-dependent chromatin remodeling complexes containing SWI/SNF proteins is described. Rotationally phased mononucleosome particles were assembledin vitroand used to demonstrate that human SWI/SNF complexes and the yeast RNA polymerase II holoenzyme, which contains yeast SWI/SNF proteins, can directly alter nucleosome structure in an ATP-dependent manner. A functional consequence of this nucleosome disruption is that the pol II general transcription factor, TATA binding protein (TBP), which cannot bind to unaltered nucleosomal DNA, can bind to its site on the altered nucleosome. This experimental system has been invaluable for characterization of both nucleosome alteration and facilitated transcription factor binding mediated by SWI/SNF complexes. These procedures should also be useful to examine other factors that interact with or structurally affect nucleosome particles." @default.
- W2023178859 created "2016-06-24" @default.
- W2023178859 creator A5032067317 @default.
- W2023178859 date "1998-08-01" @default.
- W2023178859 modified "2023-10-03" @default.
- W2023178859 title "SWI/SNF Complexes and Facilitation of TATA Binding Protein:Nucleosome Interactions" @default.
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- W2023178859 cites W1584200049 @default.
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- W2023178859 cites W1644639391 @default.
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- W2023178859 doi "https://doi.org/10.1006/meth.1998.0634" @default.
- W2023178859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9740718" @default.
- W2023178859 hasPublicationYear "1998" @default.
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