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- W2023187749 startingPage "2448" @default.
- W2023187749 abstract "Cu-catalyzed aerobic oxidative three-component coupling of a terminal alkyne, secondary amine, and sulfonamide enables efficient synthesis of amidines. The use of Cu(OTf)2 (5 mol %) produces amidines selectively without Glaser–Hay alkyne homocoupling products. Preliminary studies suggest that the reaction pathway involves initial oxidative coupling of the terminal alkyne with the secondary amine, followed by hydroamidation of the ynamine intermediate with the sulfonamide." @default.
- W2023187749 created "2016-06-24" @default.
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- W2023187749 date "2015-01-30" @default.
- W2023187749 modified "2023-10-07" @default.
- W2023187749 title "Cu-Catalyzed Aerobic Oxidative Three-Component Coupling Route to <i>N</i>-Sulfonyl Amidines via an Ynamine Intermediate" @default.
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- W2023187749 doi "https://doi.org/10.1021/jo5029198" @default.
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