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• W2023188921 abstract "<h2>Abstract</h2> <i>Purpose</i>. This study was designed to compare the frequency of postoperative epilepsy in patients with acute and chronic pre-operative epilepsy and with frontal or temporal lobe glial tumors based on the hypothesis that patients with chronic epilepsy do worse. <i>Methods</i>. We compared the clinical and diagnostic characteristics of the patients (<i>n</i>=73) who had seizures preoperatively with those of the patients (<i>n</i>=153) who did not. Among those who have had seizures preoperatively, we compared those (<i>n</i>=32, chronic seizure group) who had seizures a year or more prior to surgery with those (<i>n</i>=41, acute seizure group) who had seizures less than a year prior to surgery. <i>Results</i>. Among the various factors, the frequency of benign pathology and favorable neurological state were higher in the seizure group than in the non-seizure group (<i>p</i><0.05). Complex partial seizures and low-grade tumors were frequent in the chronic seizure group, whereas simple partial seizures and high-grade tumors were frequent in the acute seizure group. Seizure-free rate was significantly higher in the acute seizure group than in the chronic group (<i>p</i><0.05). Also, the difference of seizure control rate between surgical strategies was statistically significant (<i>p</i><0.05). <i>Conclusion</i>. This study indicates that preoperative seizure duration and frequency have a close relationship with the frequency of postoperative epilepsy in patients with glial tumors. A longer duration may allow the formation of epileptogenic foci, leading to chronic epilepsy, and eventually have a negative effect on the prognosis of the patients. Factors including histopathological characteristics of the tumor, its location, seizure duration/frequency, and symptomatology should be taken into account when deciding on surgical strategies." @default.
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• W2023188921 date "2004-09-01" @default.
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• W2023188921 title "Significance of chronic epilepsy in glial tumors and correlation with surgical strategies" @default.
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• W2023188921 doi "https://doi.org/10.1016/j.jocn.2003.09.018" @default.
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