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- W2023188947 abstract "1. The synthesis of carbon-14 labelled acetylcholine ((14)C-ACh) from carbon-14 uniformly labelled glucose (U.L. (14)C-glucose) under different conditions has been studied.2. Increasing KCl concentration from 4 mM to 31 mM was associated with a large increase in the amount of (14)C-ACh in the medium and a significant decrease in the amount of (14)C-ACh in the tissue. This effect was observed in slices and minces but not in homogenate.3. Increasing KCl concentration from 4 mM to 31 mM resulted in the release of pre-formed (14)C-ACh.4. Elevated pre-incubation levels of ACh in slices incubated in 4 mM KCl medium was associated with a decrease in the formation of (14)C-ACh.5. These findings are consistent with the hypothesis that the concentration of ACh in the vicinity of the site of synthesis regulates the rate of ACh formation." @default.
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- W2023188947 date "1969-06-01" @default.
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- W2023188947 title "Relationship between acetylcholine synthesis and its concentration in rat cerebral cortex" @default.
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- W2023188947 doi "https://doi.org/10.1111/j.1476-5381.1969.tb09512.x" @default.
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