Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023200320> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2023200320 abstract "Rabbit kidney cortex tissue slices were made ischemic (37 degrees C) for 60 min and then either reperfused in warm (37 degrees C) oxygenated physiologic buffer for 210 min or placed in UW Na gluconate solution (+/- quinacrine; 100 micromol/L) for 18 h followed by warm aerobic reperfusion. Slices were sampled at intervals and analyzed for malondialdehyde (MDA) content by HPLC. Control (nonischemic) slices had no change in MDA content over the duration of the experiment. Hypothermic storage of nonischemic slices did not result in any increase in MDA during reperfusion. Ischemic slices showed significant increases in MDA content during the first 1.5 h of reperfusion and remained elevated for the remainder of the experiment. Hypothermic storage of warm ischemic kidney slices resulted in a significant decrease in MDA content during the storage period. However, MDA content in these slices increased during warm reperfusion and was significantly higher than that in nonischemic controls. Quinacrine added during hypothermic storage of warm ischemic slices significantly decreased slice MDA content during warm reperfusion, an effect which was lost by increasing the storage solution calcium content. This study shows that aerobic hypothermic storage can aid in reducing oxidative stress in warm ischemic kidney tissue during reperfusion. This study suggests that the effects of quinacrine are at the level of the mitochondrion and not as an antioxidant compound." @default.
- W2023200320 created "2016-06-24" @default.
- W2023200320 creator A5002491487 @default.
- W2023200320 creator A5085428806 @default.
- W2023200320 date "1999-11-01" @default.
- W2023200320 modified "2023-09-27" @default.
- W2023200320 title "The Effect of Quinacrine on Oxidative Stress in Kidney Tissue Stored at Low Temperature after Warm Ischemic Injury" @default.
- W2023200320 cites W1571407612 @default.
- W2023200320 cites W1641883648 @default.
- W2023200320 cites W1963561745 @default.
- W2023200320 cites W1963764092 @default.
- W2023200320 cites W1975097027 @default.
- W2023200320 cites W1977901128 @default.
- W2023200320 cites W1978854613 @default.
- W2023200320 cites W1978870919 @default.
- W2023200320 cites W1994883935 @default.
- W2023200320 cites W1997105663 @default.
- W2023200320 cites W2005491449 @default.
- W2023200320 cites W2016486229 @default.
- W2023200320 cites W2029171127 @default.
- W2023200320 cites W2035021390 @default.
- W2023200320 cites W2039633440 @default.
- W2023200320 cites W2040529030 @default.
- W2023200320 cites W2062125339 @default.
- W2023200320 cites W2063385957 @default.
- W2023200320 cites W2064762440 @default.
- W2023200320 cites W2065441451 @default.
- W2023200320 cites W2070263356 @default.
- W2023200320 cites W2087598382 @default.
- W2023200320 cites W2117909173 @default.
- W2023200320 cites W2149453782 @default.
- W2023200320 cites W2156136640 @default.
- W2023200320 cites W2158009878 @default.
- W2023200320 cites W2399468662 @default.
- W2023200320 cites W2405361583 @default.
- W2023200320 doi "https://doi.org/10.1006/cryo.1999.2198" @default.
- W2023200320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10600253" @default.
- W2023200320 hasPublicationYear "1999" @default.
- W2023200320 type Work @default.
- W2023200320 sameAs 2023200320 @default.
- W2023200320 citedByCount "5" @default.
- W2023200320 crossrefType "journal-article" @default.
- W2023200320 hasAuthorship W2023200320A5002491487 @default.
- W2023200320 hasAuthorship W2023200320A5085428806 @default.
- W2023200320 hasConcept C134018914 @default.
- W2023200320 hasConcept C185592680 @default.
- W2023200320 hasConcept C2776151105 @default.
- W2023200320 hasConcept C2778401633 @default.
- W2023200320 hasConcept C2780091579 @default.
- W2023200320 hasConcept C55493867 @default.
- W2023200320 hasConcept C71924100 @default.
- W2023200320 hasConceptScore W2023200320C134018914 @default.
- W2023200320 hasConceptScore W2023200320C185592680 @default.
- W2023200320 hasConceptScore W2023200320C2776151105 @default.
- W2023200320 hasConceptScore W2023200320C2778401633 @default.
- W2023200320 hasConceptScore W2023200320C2780091579 @default.
- W2023200320 hasConceptScore W2023200320C55493867 @default.
- W2023200320 hasConceptScore W2023200320C71924100 @default.
- W2023200320 hasLocation W20232003201 @default.
- W2023200320 hasLocation W20232003202 @default.
- W2023200320 hasOpenAccess W2023200320 @default.
- W2023200320 hasPrimaryLocation W20232003201 @default.
- W2023200320 hasRelatedWork W1835107514 @default.
- W2023200320 hasRelatedWork W1981013632 @default.
- W2023200320 hasRelatedWork W1985317751 @default.
- W2023200320 hasRelatedWork W1987107444 @default.
- W2023200320 hasRelatedWork W1996552987 @default.
- W2023200320 hasRelatedWork W1999416658 @default.
- W2023200320 hasRelatedWork W2005491449 @default.
- W2023200320 hasRelatedWork W2025722744 @default.
- W2023200320 hasRelatedWork W2047861107 @default.
- W2023200320 hasRelatedWork W2055222758 @default.
- W2023200320 hasRelatedWork W2063549246 @default.
- W2023200320 hasRelatedWork W2068586120 @default.
- W2023200320 hasRelatedWork W2070447105 @default.
- W2023200320 hasRelatedWork W2084437167 @default.
- W2023200320 hasRelatedWork W2415622024 @default.
- W2023200320 hasRelatedWork W2416854953 @default.
- W2023200320 hasRelatedWork W2431667048 @default.
- W2023200320 hasRelatedWork W2439707311 @default.
- W2023200320 hasRelatedWork W2794509907 @default.
- W2023200320 hasRelatedWork W3142677336 @default.
- W2023200320 isParatext "false" @default.
- W2023200320 isRetracted "false" @default.
- W2023200320 magId "2023200320" @default.
- W2023200320 workType "article" @default.