FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023201233> ?p ?o ?g. }

• W2023201233 endingPage "956" @default.
• W2023201233 startingPage "950" @default.
• W2023201233 abstract "<h3>Background:</h3> Skeletal muscle wasting commonly occurs in patients with chronic obstructive pulmonary disease (COPD) and has been associated with the presence of systemic inflammation. This study investigated whether rehabilitative exercise training decreases the levels of systemic or local muscle inflammation or reverses the abnormalities associated with muscle deconditioning. <h3>Methods:</h3> Fifteen patients with COPD (mean (SE) forced expiratory volume in 1 s 36 (4)% predicted) undertook high-intensity exercise training 3 days/week for 10 weeks. Before and after the training programme the concentration of tumour necrosis factor α (TNFα), interleukin-6 (IL-6) and C-reactive protein (CRP) in plasma was determined by ELISA, and vastus lateralis mRNA expression of TNFα, IL-6, total insulin-like growth factor-I (IGF-I) and its isoform mechanogrowth factor (MGF) and myogenic differentiation factor D (MyoD) were assessed by real-time PCR. Protein levels of TNFα, IGF-I and MyoD were measured by Western blotting. <h3>Results:</h3> Rehabilitation improved peak exercise work rate by 10 (2%) (p = 0.004) and mean fibre cross-sectional area from 4061 (254) μm² to 4581 (241) μm² (p = 0.001). Plasma inflammatory mediators and vastus lateralis expression of TNFα and IL-6 were not significantly modified by training. In contrast, there was a significant increase in mRNA expression of IGF-I (by 67 (22)%; p = 0.044), MGF (by 67 (15)%; p = 0.002) and MyoD (by 116 (30)%; p = 0.001). The increase observed at the mRNA level was also seen at the protein level for IGF-I (by 72 (36)%; p = 0.046) and MyoD (by 67 (21)%; p = 0.012). <h3>Conclusions:</h3> Pulmonary rehabilitation can induce peripheral muscle adaptations and modifications in factors regulating skeletal muscle hypertrophy and regeneration without decreasing the levels of systemic or local muscle inflammation." @default.
• W2023201233 created "2016-06-24" @default.
• W2023201233 creator A5001375020 @default.
• W2023201233 creator A5015268511 @default.
• W2023201233 creator A5015585526 @default.
• W2023201233 creator A5054698240 @default.
• W2023201233 creator A5056739553 @default.
• W2023201233 creator A5059236085 @default.
• W2023201233 creator A5064261287 @default.
• W2023201233 date "2007-05-25" @default.
• W2023201233 modified "2023-10-11" @default.
• W2023201233 title "Effects of rehabilitative exercise on peripheral muscle TNF , IL-6, IGF-I and MyoD expression in patients with COPD" @default.
• W2023201233 cites W1905314305 @default.
• W2023201233 cites W1910033896 @default.
• W2023201233 cites W1964906652 @default.
• W2023201233 cites W1972588215 @default.
• W2023201233 cites W1980988188 @default.
• W2023201233 cites W1982435260 @default.
• W2023201233 cites W2004008756 @default.
• W2023201233 cites W2010081999 @default.
• W2023201233 cites W2015263591 @default.
• W2023201233 cites W2017429680 @default.
• W2023201233 cites W2023561026 @default.
• W2023201233 cites W2030972258 @default.
• W2023201233 cites W2041812937 @default.
• W2023201233 cites W2043236663 @default.
• W2023201233 cites W2045616259 @default.
• W2023201233 cites W2057070304 @default.
• W2023201233 cites W2061475229 @default.
• W2023201233 cites W2077218757 @default.
• W2023201233 cites W2079843433 @default.
• W2023201233 cites W2080710138 @default.
• W2023201233 cites W2088802642 @default.
• W2023201233 cites W2102139058 @default.
• W2023201233 cites W2108122217 @default.
• W2023201233 cites W2108811145 @default.
• W2023201233 cites W2114423036 @default.
• W2023201233 cites W2121051855 @default.
• W2023201233 cites W2121311831 @default.
• W2023201233 cites W2123064842 @default.
• W2023201233 cites W2127101512 @default.
• W2023201233 cites W2132829439 @default.
• W2023201233 cites W2134062132 @default.
• W2023201233 cites W2142817780 @default.
• W2023201233 cites W2147640669 @default.
• W2023201233 cites W2160050642 @default.
• W2023201233 cites W2161114559 @default.
• W2023201233 cites W2161820702 @default.
• W2023201233 cites W2170003225 @default.
• W2023201233 cites W2171215026 @default.
• W2023201233 cites W2171872390 @default.
• W2023201233 doi "https://doi.org/10.1136/thx.2006.069310" @default.
• W2023201233 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2117139" @default.
• W2023201233 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17573449" @default.
• W2023201233 hasPublicationYear "2007" @default.
• W2023201233 type Work @default.
• W2023201233 sameAs 2023201233 @default.
• W2023201233 citedByCount "113" @default.
• W2023201233 countsByYear W20232012332012 @default.
• W2023201233 countsByYear W20232012332013 @default.
• W2023201233 countsByYear W20232012332014 @default.
• W2023201233 countsByYear W20232012332015 @default.
• W2023201233 countsByYear W20232012332016 @default.
• W2023201233 countsByYear W20232012332017 @default.
• W2023201233 countsByYear W20232012332018 @default.
• W2023201233 countsByYear W20232012332019 @default.
• W2023201233 countsByYear W20232012332020 @default.
• W2023201233 countsByYear W20232012332021 @default.
• W2023201233 countsByYear W20232012332022 @default.
• W2023201233 countsByYear W20232012332023 @default.
• W2023201233 crossrefType "journal-article" @default.
• W2023201233 hasAuthorship W2023201233A5001375020 @default.
• W2023201233 hasAuthorship W2023201233A5015268511 @default.
• W2023201233 hasAuthorship W2023201233A5015585526 @default.
• W2023201233 hasAuthorship W2023201233A5054698240 @default.
• W2023201233 hasAuthorship W2023201233A5056739553 @default.
• W2023201233 hasAuthorship W2023201233A5059236085 @default.
• W2023201233 hasAuthorship W2023201233A5064261287 @default.
• W2023201233 hasBestOaLocation W20232012331 @default.
• W2023201233 hasConcept C126322002 @default.
• W2023201233 hasConcept C134018914 @default.
• W2023201233 hasConcept C170493617 @default.
• W2023201233 hasConcept C17991360 @default.
• W2023201233 hasConcept C2775960820 @default.
• W2023201233 hasConcept C2776252253 @default.
• W2023201233 hasConcept C2776263037 @default.
• W2023201233 hasConcept C2776780178 @default.
• W2023201233 hasConcept C2776914184 @default.
• W2023201233 hasConcept C2778106681 @default.
• W2023201233 hasConcept C2779959927 @default.
• W2023201233 hasConcept C2780689927 @default.
• W2023201233 hasConcept C3763915 @default.
• W2023201233 hasConcept C71924100 @default.
• W2023201233 hasConceptScore W2023201233C126322002 @default.
• W2023201233 hasConceptScore W2023201233C134018914 @default.
• W2023201233 hasConceptScore W2023201233C170493617 @default.
• W2023201233 hasConceptScore W2023201233C17991360 @default.
• W2023201233 hasConceptScore W2023201233C2775960820 @default.

• next