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- W2023201279 abstract "The effect of the novel non-peptide neuropeptide Y Y1 receptor antagonist BIBP3226, N2-(diphenylacetyl)-N-[(4-hydroxy-phenyl)-methyl]-D-arginine amide, on exploratory behaviour of rats in the elevated plus-maze was studied. BIBP3226 (0.5 and 5 micrograms, i.c.v.) induced an anxiogenic-like effect at the higher dose tested. This effect was antagonised by diazepam (0.5 mg/kg). The anxiogenic-like effect of BIBP3226 was not related to a decrease in general locomotor activity. These findings support the hypothesis that neuropeptide Y Y1 receptor subtype is involved in anxiety regulation." @default.
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- W2023201279 date "1996-12-01" @default.
- W2023201279 modified "2023-09-27" @default.
- W2023201279 title "Anxiogenic-like effect of the neuropeptide Y Y1 receptor antagonist BIBP3226: antagonism with diazepam" @default.
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- W2023201279 doi "https://doi.org/10.1016/s0014-2999(96)00838-2" @default.
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