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• W2023202040 abstract "An abnormal isoform of prion protein (PrPSc) was extracted from formalin-fixed paraffin-embedded (FFPE) tissues from sheep and analyzed by western blotting. PrPSc immunoreactivity against anti-PrP monoclonal antibody T2, which recognizes discontinuous PrP sequences, differed amongst individual scrapie sheep cases. This may reflect structural differences in PrPSc that have been formalin-fixed prior to their extraction. This study indicates that western blotting by using FFPE tissues is useful for the retrospective analysis of transmissible spongiform encephalopathies in which only formalin-fixed samples are available and in conducting transmissible spongiform encephalopathies surveillance where freezing system is insufficient." @default.
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• W2023202040 date "2012-01-01" @default.
• W2023202040 modified "2023-10-16" @default.
• W2023202040 title "Retrospective Analysis of Sheep Scrapie by Western Blotting with Formalin-Fixed Paraffin-Embedded (FFPE) Tissues" @default.
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• W2023202040 doi "https://doi.org/10.1292/jvms.12-0037" @default.
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