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- W2023207849 abstract "A novel heparan sulfate disaccharide fluoride derivative of GlcN(SO3Na)α(1 → 4)GlcAβ-F (1) was designed as a probe for detection of heparanase activity. Compound 1 was successfully prepared via 10-step chemical reactions. Human heparanase-1 effectively recognized 1, which induced liberation of the fluoride ion by hydrolysis via enzyme catalysis. The hydrolysis reaction was easily monitored by 1H NMR measurements, in which the signal from H-1 gradually disappeared." @default.
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- W2023207849 date "2013-10-05" @default.
- W2023207849 modified "2023-09-26" @default.
- W2023207849 title "Synthesis of a Heparan Sulfate Disaccharide Fluoride for Detection of Heparanase Activity" @default.
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- W2023207849 doi "https://doi.org/10.1246/cl.130437" @default.
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