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- W2023210232 abstract "Recently, Beaulieu et al. (2012) published an article (TG-186) providing guidance for Medical-Based Dose Calculation Algorithms (MBDCAs), where tissue heterogeneity considerations are addressed. It is well-known that TG-43U1 (Rivard et al., 2004) formalism which considers only water medium is limited and significant dose differences have been found comparing both methodologies. The aim of the present work is to experimentally quantify dose values in heterogeneous medium. All experiments have been simulated using the MCNP5 Monte Carlo code and performed using radiochromic films, TLDs and MOSFETs within heterogeneous phantoms composed by PMMA, lung, muscle, adipose tissue, breast and 2 types of bone. Film dosimetry has been performed using two methodologies: a) linearization for dose-response curve (Devic and Tomic, 2012) based on calibration curves to create a functional form that linearizes the dose response and b) multichannel analysis dosimetry (Micke et al., 2011). Comparison of experimental results are in good agreement with calculated dose values with MCNP5 with maximum discrepancies less than 10% for all dosimeters. Film multichannel analysis dosimetry allowed to address not only disturbances in the measurements caused by thickness variation in the film active layer, but also, separate other external influences in the dose while the liberalization method reduced considerably the experimental uncertainty be avoiding the calibration procedure. High accuracy dosimetry can be performed using brachytherapy sources even when dose measurements are highly sensitive to experimental uncertainties due to high dose gradient and may lead to large errors when well defined measurement protocols are not followed for each dosimeter." @default.
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- W2023210232 date "2014-03-01" @default.
- W2023210232 modified "2023-10-18" @default.
- W2023210232 title "Dose Measurements for an Ir-192 Source Using Mosfets, Radiochromic Films, TLDs and Heterogeneous Tissues" @default.
- W2023210232 doi "https://doi.org/10.1016/j.brachy.2014.02.388" @default.
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