FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023221851> ?p ?o ?g. }

• W2023221851 endingPage "1290" @default.
• W2023221851 startingPage "1283" @default.
• W2023221851 abstract "Persistence of bovine Staphylococcus aureus mastitis may be associated with the small colony variant (SCV) form that is adapted to intracellular life and resists elimination by the immune system. This study evaluated antibody-mediated (AMIR) and cell-mediated immune responses (CMIR) to two bovine SCV forms and their parent strains isolated from cows with mastitis. Four groups of healthy cows, five cows/treatment group, were challenged by the intramammary route with naturally occurring bovine SCV Heba3231, its parent strain 3231, a hemB mutant displaying the SCV phenotype or its parent strain, Newbould 305. Blood and milk samples were collected at day 0 before challenge and at days 1, 14, 21 and 36 post-challenge to determine antigen-specific immunoglobulin (Ig) IgG(1) and IgG(2) antibody responses as indicators of type 2 and type 1 responses, respectively. At day 24 post-challenge cows in each group were inoculated with the UV-killed homologous strain intradermally in the neck to induce delayed-type hypersensitivity (DTH) as an indicator of CMIR. The SCV Heba3231 and 3231 strains induced significant IgG(1) and IgG(2) antibody responses in sera and in sera and milk whey, respectively. The hemB SCV mutant and Newbould 305 strains induced significant IgG(1) antibody in milk whey, and in sera and milk whey, respectively. The SCV Heba3231 and 3231 strains induced DTH, the hemB mutant induced intermediate hypersensitivity, and Newbould 305 failed to induce DTH. These results indicate marked differences in immune responses induced by parent and SCV forms of the same strain of S. aureus and by the two wild-type strains. This is the first study to evaluate both AMIR and CMIR in the context of persistent bovine mastitis to different and genetically characterized strains of S. aureus including two SCVs. The findings expand our understanding of immune responses to persistent S. aureus mastitis." @default.
• W2023221851 created "2016-06-24" @default.
• W2023221851 creator A5010953970 @default.
• W2023221851 creator A5023092356 @default.
• W2023221851 creator A5028593821 @default.
• W2023221851 creator A5048018579 @default.
• W2023221851 creator A5086017714 @default.
• W2023221851 creator A5091071071 @default.
• W2023221851 date "2010-12-01" @default.
• W2023221851 modified "2023-09-25" @default.
• W2023221851 title "Antibody and cell-mediated immune responses to Staphylococcus aureus small colony variants and their parental strains associated with bovine mastitis" @default.
• W2023221851 cites W128879804 @default.
• W2023221851 cites W1494205829 @default.
• W2023221851 cites W167442780 @default.
• W2023221851 cites W1963931264 @default.
• W2023221851 cites W1976080712 @default.
• W2023221851 cites W1978087809 @default.
• W2023221851 cites W1982843922 @default.
• W2023221851 cites W1983821024 @default.
• W2023221851 cites W2006048645 @default.
• W2023221851 cites W2013558611 @default.
• W2023221851 cites W2019207264 @default.
• W2023221851 cites W2020465764 @default.
• W2023221851 cites W2025475092 @default.
• W2023221851 cites W2028387909 @default.
• W2023221851 cites W2029935265 @default.
• W2023221851 cites W2035158252 @default.
• W2023221851 cites W2045492356 @default.
• W2023221851 cites W204987735 @default.
• W2023221851 cites W2063962293 @default.
• W2023221851 cites W2064737440 @default.
• W2023221851 cites W2064752366 @default.
• W2023221851 cites W2070126656 @default.
• W2023221851 cites W2086427349 @default.
• W2023221851 cites W2088960594 @default.
• W2023221851 cites W2089074678 @default.
• W2023221851 cites W2089833870 @default.
• W2023221851 cites W2096281354 @default.
• W2023221851 cites W2123345218 @default.
• W2023221851 cites W2127842687 @default.
• W2023221851 cites W2128587227 @default.
• W2023221851 cites W2134051473 @default.
• W2023221851 cites W2137980986 @default.
• W2023221851 cites W2138870096 @default.
• W2023221851 cites W2141580300 @default.
• W2023221851 cites W2160049798 @default.
• W2023221851 cites W2166054948 @default.
• W2023221851 cites W2169002049 @default.
• W2023221851 cites W2204330157 @default.
• W2023221851 cites W2395692098 @default.
• W2023221851 cites W2917737494 @default.
• W2023221851 cites W4244416687 @default.
• W2023221851 cites W4249464132 @default.
• W2023221851 doi "https://doi.org/10.1016/j.dci.2010.07.005" @default.
• W2023221851 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20670645" @default.
• W2023221851 hasPublicationYear "2010" @default.
• W2023221851 type Work @default.
• W2023221851 sameAs 2023221851 @default.
• W2023221851 citedByCount "20" @default.
• W2023221851 countsByYear W20232218512012 @default.
• W2023221851 countsByYear W20232218512013 @default.
• W2023221851 countsByYear W20232218512014 @default.
• W2023221851 countsByYear W20232218512015 @default.
• W2023221851 countsByYear W20232218512016 @default.
• W2023221851 countsByYear W20232218512017 @default.
• W2023221851 countsByYear W20232218512021 @default.
• W2023221851 countsByYear W20232218512022 @default.
• W2023221851 countsByYear W20232218512023 @default.
• W2023221851 crossrefType "journal-article" @default.
• W2023221851 hasAuthorship W2023221851A5010953970 @default.
• W2023221851 hasAuthorship W2023221851A5023092356 @default.
• W2023221851 hasAuthorship W2023221851A5028593821 @default.
• W2023221851 hasAuthorship W2023221851A5048018579 @default.
• W2023221851 hasAuthorship W2023221851A5086017714 @default.
• W2023221851 hasAuthorship W2023221851A5091071071 @default.
• W2023221851 hasConcept C147483822 @default.
• W2023221851 hasConcept C159654299 @default.
• W2023221851 hasConcept C203014093 @default.
• W2023221851 hasConcept C2776344049 @default.
• W2023221851 hasConcept C2779489039 @default.
• W2023221851 hasConcept C2780898057 @default.
• W2023221851 hasConcept C523546767 @default.
• W2023221851 hasConcept C54355233 @default.
• W2023221851 hasConcept C86803240 @default.
• W2023221851 hasConcept C8891405 @default.
• W2023221851 hasConcept C89423630 @default.
• W2023221851 hasConceptScore W2023221851C147483822 @default.
• W2023221851 hasConceptScore W2023221851C159654299 @default.
• W2023221851 hasConceptScore W2023221851C203014093 @default.
• W2023221851 hasConceptScore W2023221851C2776344049 @default.
• W2023221851 hasConceptScore W2023221851C2779489039 @default.
• W2023221851 hasConceptScore W2023221851C2780898057 @default.
• W2023221851 hasConceptScore W2023221851C523546767 @default.
• W2023221851 hasConceptScore W2023221851C54355233 @default.
• W2023221851 hasConceptScore W2023221851C86803240 @default.
• W2023221851 hasConceptScore W2023221851C8891405 @default.
• W2023221851 hasConceptScore W2023221851C89423630 @default.
• W2023221851 hasIssue "12" @default.

• next