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- W2023225943 abstract "An inducible hemolysin with antibacterial properties was isolated from the hemolymph of immune Galleria mellonella larvae. The Galleria-derived lysin, named Gallysin-1, was shown to have an apparent molecular weight of 75,000 and to be relatively heat stable at 56°C. Although Gallysin alone was not bactericidal it caused sufficient damage of the outer cell membranes of Pseudomonas aeruginosa RP4 and Escherichia coli K176 to release β-lactamase from the periplasm. In the presence of either purified Galleria lysozyme or egg white lysozyme Gallysin-1 had potent antibacterial activity against gram-negative bacteria. Gallysin-1 killed osmotically shocked P. aeruginosa and E. coli that suggests that it can also attack exposed inner cell membranes of gramnegative bacteria. The identification of Gallysin-1 recognizes another distinct member of the bactericidins involved in insect immunity." @default.
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- W2023225943 title "Gallysin-1, an antibacterial protein isolated from hemolymph of Galleria mellonella" @default.
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- W2023225943 doi "https://doi.org/10.1016/0145-305x(94)90248-8" @default.
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