Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023226506> ?p ?o ?g. }
- W2023226506 endingPage "42" @default.
- W2023226506 startingPage "35" @default.
- W2023226506 abstract "Octanoyltransferases (LIP2) are important for the lipoylation of several α-ketoacid decarboxylases and glycine decarboxylase, all of which are essential multienzyme complexes of central metabolism, by attaching de novo-synthesised octanoyl moieties to the respective target subunits. Lipoyl synthase (LIP1) then inserts two sulphur atoms each into the protein-bound octanoyl chains to generate the functional lipoamide arms. In plants, most of the above multienzyme complexes occur only in mitochondria. Pyruvate dehydrogenase is an exception, since it also occurs in plastids. Plastidial LIP1 and LIP2 are known, but it is not clear how essential these enzymes are. Here, we report that not just one but two redundant LIP2 isoforms, LIP2p and LIP2p2, operate in plastids of Arabidopsis. The combined deletion of the two isoenzymes is embryo-lethal. Deletion of the plastidial lipoyl synthase LIP1p is also embryo-lethal, indicating that all plastidial LIP1 activity is due to LIP1p. These features suggest that protein lipoylation is based on an autonomous and partially redundant de novo lipoylation pathway in plastids." @default.
- W2023226506 created "2016-06-24" @default.
- W2023226506 creator A5015089278 @default.
- W2023226506 creator A5051590888 @default.
- W2023226506 creator A5053862310 @default.
- W2023226506 creator A5081871178 @default.
- W2023226506 date "2013-04-15" @default.
- W2023226506 modified "2023-09-24" @default.
- W2023226506 title "Two redundant octanoyltransferases and one obligatory lipoyl synthase provide protein-lipoylation autonomy to plastids of<i>Arabidopsis</i>" @default.
- W2023226506 cites W1527284807 @default.
- W2023226506 cites W1551668099 @default.
- W2023226506 cites W1556287700 @default.
- W2023226506 cites W1565494682 @default.
- W2023226506 cites W1569916206 @default.
- W2023226506 cites W1607291127 @default.
- W2023226506 cites W1653996640 @default.
- W2023226506 cites W1965286519 @default.
- W2023226506 cites W1971620137 @default.
- W2023226506 cites W1978189929 @default.
- W2023226506 cites W1995886567 @default.
- W2023226506 cites W1998527566 @default.
- W2023226506 cites W2001986473 @default.
- W2023226506 cites W2006395081 @default.
- W2023226506 cites W2016392215 @default.
- W2023226506 cites W2021819812 @default.
- W2023226506 cites W2025003758 @default.
- W2023226506 cites W2042301495 @default.
- W2023226506 cites W2043151685 @default.
- W2023226506 cites W2043330551 @default.
- W2023226506 cites W2050338175 @default.
- W2023226506 cites W2056097713 @default.
- W2023226506 cites W2064472901 @default.
- W2023226506 cites W2069305607 @default.
- W2023226506 cites W2075253085 @default.
- W2023226506 cites W2078823622 @default.
- W2023226506 cites W2092152103 @default.
- W2023226506 cites W2095347327 @default.
- W2023226506 cites W2095753590 @default.
- W2023226506 cites W2098115340 @default.
- W2023226506 cites W2100837269 @default.
- W2023226506 cites W2101507022 @default.
- W2023226506 cites W2102002238 @default.
- W2023226506 cites W2109388404 @default.
- W2023226506 cites W2110958932 @default.
- W2023226506 cites W2116382358 @default.
- W2023226506 cites W2125332243 @default.
- W2023226506 cites W2129095580 @default.
- W2023226506 cites W2129640685 @default.
- W2023226506 cites W2142512902 @default.
- W2023226506 cites W2151965879 @default.
- W2023226506 cites W2160822774 @default.
- W2023226506 cites W233398006 @default.
- W2023226506 cites W288081691 @default.
- W2023226506 cites W4293247451 @default.
- W2023226506 doi "https://doi.org/10.1111/plb.12028" @default.
- W2023226506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23581459" @default.
- W2023226506 hasPublicationYear "2013" @default.
- W2023226506 type Work @default.
- W2023226506 sameAs 2023226506 @default.
- W2023226506 citedByCount "12" @default.
- W2023226506 countsByYear W20232265062014 @default.
- W2023226506 countsByYear W20232265062016 @default.
- W2023226506 countsByYear W20232265062019 @default.
- W2023226506 countsByYear W20232265062020 @default.
- W2023226506 countsByYear W20232265062021 @default.
- W2023226506 countsByYear W20232265062022 @default.
- W2023226506 countsByYear W20232265062023 @default.
- W2023226506 crossrefType "journal-article" @default.
- W2023226506 hasAuthorship W2023226506A5015089278 @default.
- W2023226506 hasAuthorship W2023226506A5051590888 @default.
- W2023226506 hasAuthorship W2023226506A5053862310 @default.
- W2023226506 hasAuthorship W2023226506A5081871178 @default.
- W2023226506 hasConcept C104317684 @default.
- W2023226506 hasConcept C112243037 @default.
- W2023226506 hasConcept C143065580 @default.
- W2023226506 hasConcept C181199279 @default.
- W2023226506 hasConcept C2779491563 @default.
- W2023226506 hasConcept C55493867 @default.
- W2023226506 hasConcept C69305403 @default.
- W2023226506 hasConcept C86803240 @default.
- W2023226506 hasConcept C93829228 @default.
- W2023226506 hasConceptScore W2023226506C104317684 @default.
- W2023226506 hasConceptScore W2023226506C112243037 @default.
- W2023226506 hasConceptScore W2023226506C143065580 @default.
- W2023226506 hasConceptScore W2023226506C181199279 @default.
- W2023226506 hasConceptScore W2023226506C2779491563 @default.
- W2023226506 hasConceptScore W2023226506C55493867 @default.
- W2023226506 hasConceptScore W2023226506C69305403 @default.
- W2023226506 hasConceptScore W2023226506C86803240 @default.
- W2023226506 hasConceptScore W2023226506C93829228 @default.
- W2023226506 hasFunder F4320320879 @default.
- W2023226506 hasIssue "1" @default.
- W2023226506 hasLocation W20232265061 @default.
- W2023226506 hasLocation W20232265062 @default.
- W2023226506 hasOpenAccess W2023226506 @default.
- W2023226506 hasPrimaryLocation W20232265061 @default.
- W2023226506 hasRelatedWork W1465188717 @default.
- W2023226506 hasRelatedWork W1596154245 @default.