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- W2023229062 abstract "To confirm the findings of uncontrolled trials that methylprednisolone pulse therapy (MPPT) is a safe treatment for active rheumatoid disease, a double-blind trial was conducted in which 20 patients with active rheumatoid disease were randomly allocated to receive an infusion of either 1 g methylprednisolone or placebo. Methylprednisolone produced significant improvement in all clinical variables measured, a benefit which was sustained for at least 6 weeks. The placebo produced only transient improvement in some of the clinical variables measured. when the 10 placebo groups patients were later given an infusion of 1 g methylprednisolone, they too showed significant clinical benefit. The methylprednisolone also gave rise to improvements in some haematological and biochemical variables." @default.
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- W2023229062 date "1982-07-01" @default.
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- W2023229062 title "A DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL OF METHYLPREDNISOLONE PULSE THERAPY IN ACTIVE RHEUMATOID DISEASE" @default.
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- W2023229062 doi "https://doi.org/10.1016/s0140-6736(82)90323-3" @default.
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