FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023237068> ?p ?o ?g. }

• W2023237068 endingPage "315" @default.
• W2023237068 startingPage "311" @default.
• W2023237068 abstract "Back-scattered electron microscopy was used to study mineralization levels of human iliac cancellous bone of white females (N = 49). Mineralization levels were assessed by converting bone pixel grayscale levels to atomic number (Z) using known calibration standards. The data set consisted of bone biopsies from normal and vertebral fracture subjects that had either high or low values for bone formation rate (BFR(s)) within their respective groups (fracture/low BFR(s), N = 12; fracture/high BFR(s), N = 10; normal/low BFR(s), N = 12; normal/high BFR(s), N = 15). The following three measures of mineralization were quantitatively determined for each specimen: an overall mean mineralization (Z(mean)), the mineralization of trabecular packets deep within the interior of trabeculae (Z(deep)), and the mineralization of superficial exterior packets (Z(superficial)). Two-way analysis of variance revealed that the high BFR(s) group had a significantly lower Z(superficial) than the low BFR(s) group [mean (SD) 10.383 (0.270) vs. 10.563 (0.289)], and there was no significant interaction. BFR(s) had no effect on Z(mean) or Z(deep). For the pooled data, Z(deep) was significantly higher than Z(superficial) [10.866 (0.242) vs. 10.471 (0.291)]. There was no significant difference in Z(mean), Z(deep), or Z(superficial) between normals and those with vertebral fracture, but the standard deviations of the mineralization measures in the fracture group were at least double that of the normal group. Frequency histograms show that the two groups have fundamentally different mineralization distributions. The normal group demonstrates typical Gaussian distributions centered around the mean, and the distributions of the fracture group are bimodal, with peaks occurring at either the high or low tails of the distributions of the normal group. We hypothesize that both low and high patterns of mineralization might detrimentally affect bone material properties, with low mineralization levels causing reduced stiffness and strength and high mineralization resulting in reduced fracture toughness. The degree to which the mineralization differences may affect strength and stiffness of individual elements is estimated. The higher standard deviations of mineralization measures in the fracture group may reflect an inability to properly regulate trabecular level stress and strain. Forward stepwise regression analysis showed significant relationships between Ob.S/OS and both Z(superficial) and Z(mean), suggesting that the osteoblast may play an important role in regulating mineralization." @default.
• W2023237068 created "2016-06-24" @default.
• W2023237068 creator A5019250338 @default.
• W2023237068 creator A5049805492 @default.
• W2023237068 creator A5054118361 @default.
• W2023237068 date "2003-03-01" @default.
• W2023237068 modified "2023-10-01" @default.
• W2023237068 title "Effects of vertebral bone fragility and bone formation rate on the mineralization levels of cancellous bone from white females" @default.
• W2023237068 cites W1978906175 @default.
• W2023237068 cites W1981110957 @default.
• W2023237068 cites W1993467351 @default.
• W2023237068 cites W1996131009 @default.
• W2023237068 cites W1998631739 @default.
• W2023237068 cites W2001852594 @default.
• W2023237068 cites W2020246529 @default.
• W2023237068 cites W2028608421 @default.
• W2023237068 cites W2036940350 @default.
• W2023237068 cites W2058564535 @default.
• W2023237068 cites W2060398686 @default.
• W2023237068 cites W2069707798 @default.
• W2023237068 cites W2074806944 @default.
• W2023237068 cites W2087378917 @default.
• W2023237068 cites W2109228661 @default.
• W2023237068 cites W2131260019 @default.
• W2023237068 cites W2151744592 @default.
• W2023237068 cites W2162511894 @default.
• W2023237068 doi "https://doi.org/10.1016/s8756-3282(02)00975-4" @default.
• W2023237068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12667559" @default.
• W2023237068 hasPublicationYear "2003" @default.
• W2023237068 type Work @default.
• W2023237068 sameAs 2023237068 @default.
• W2023237068 citedByCount "134" @default.
• W2023237068 countsByYear W20232370682012 @default.
• W2023237068 countsByYear W20232370682013 @default.
• W2023237068 countsByYear W20232370682014 @default.
• W2023237068 countsByYear W20232370682015 @default.
• W2023237068 countsByYear W20232370682016 @default.
• W2023237068 countsByYear W20232370682017 @default.
• W2023237068 countsByYear W20232370682018 @default.
• W2023237068 countsByYear W20232370682019 @default.
• W2023237068 countsByYear W20232370682020 @default.
• W2023237068 countsByYear W20232370682021 @default.
• W2023237068 countsByYear W20232370682022 @default.
• W2023237068 countsByYear W20232370682023 @default.
• W2023237068 crossrefType "journal-article" @default.
• W2023237068 hasAuthorship W2023237068A5019250338 @default.
• W2023237068 hasAuthorship W2023237068A5049805492 @default.
• W2023237068 hasAuthorship W2023237068A5054118361 @default.
• W2023237068 hasConcept C105702510 @default.
• W2023237068 hasConcept C111696902 @default.
• W2023237068 hasConcept C126322002 @default.
• W2023237068 hasConcept C178790620 @default.
• W2023237068 hasConcept C185592680 @default.
• W2023237068 hasConcept C199343813 @default.
• W2023237068 hasConcept C2776350087 @default.
• W2023237068 hasConcept C2776541429 @default.
• W2023237068 hasConcept C2909674915 @default.
• W2023237068 hasConcept C3018268312 @default.
• W2023237068 hasConcept C537208039 @default.
• W2023237068 hasConcept C71924100 @default.
• W2023237068 hasConceptScore W2023237068C105702510 @default.
• W2023237068 hasConceptScore W2023237068C111696902 @default.
• W2023237068 hasConceptScore W2023237068C126322002 @default.
• W2023237068 hasConceptScore W2023237068C178790620 @default.
• W2023237068 hasConceptScore W2023237068C185592680 @default.
• W2023237068 hasConceptScore W2023237068C199343813 @default.
• W2023237068 hasConceptScore W2023237068C2776350087 @default.
• W2023237068 hasConceptScore W2023237068C2776541429 @default.
• W2023237068 hasConceptScore W2023237068C2909674915 @default.
• W2023237068 hasConceptScore W2023237068C3018268312 @default.
• W2023237068 hasConceptScore W2023237068C537208039 @default.
• W2023237068 hasConceptScore W2023237068C71924100 @default.
• W2023237068 hasIssue "3" @default.
• W2023237068 hasLocation W20232370681 @default.
• W2023237068 hasLocation W20232370682 @default.
• W2023237068 hasOpenAccess W2023237068 @default.
• W2023237068 hasPrimaryLocation W20232370681 @default.
• W2023237068 hasRelatedWork W2020309083 @default.
• W2023237068 hasRelatedWork W2023237068 @default.
• W2023237068 hasRelatedWork W2031176097 @default.
• W2023237068 hasRelatedWork W2061776718 @default.
• W2023237068 hasRelatedWork W2082801823 @default.
• W2023237068 hasRelatedWork W2133561850 @default.
• W2023237068 hasRelatedWork W2317101931 @default.
• W2023237068 hasRelatedWork W2355119082 @default.
• W2023237068 hasRelatedWork W2389030881 @default.
• W2023237068 hasRelatedWork W2989054308 @default.
• W2023237068 hasVolume "32" @default.
• W2023237068 isParatext "false" @default.
• W2023237068 isRetracted "false" @default.
• W2023237068 magId "2023237068" @default.
• W2023237068 workType "article" @default.