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- W2023237744 abstract "Putting new findings into the context of available literature knowledge is one approach to deal with the surge of high-throughput data results. Furthermore, prior knowledge can increase the performance and stability of bioinformatic algorithms, for example, methods for network reconstruction. In this review, we examine software packages for the statistical computing framework R, which enable the integration of pathway data for further bioinformatic analyses. Different approaches to integrate and visualize pathway data are identified and packages are stratified concerning their features according to a number of different aspects: data import strategies, the extent of available data, dependencies on external tools, integration with further analysis steps and visualization options are considered. A total of 12 packages integrating pathway data are reviewed in this manuscript. These are supplemented by five R-specific packages for visualization and six connector packages, which provide access to external tools." @default.
- W2023237744 created "2016-06-24" @default.
- W2023237744 creator A5010964383 @default.
- W2023237744 creator A5017944645 @default.
- W2023237744 creator A5063900707 @default.
- W2023237744 date "2014-02-07" @default.
- W2023237744 modified "2023-09-27" @default.
- W2023237744 title "R-Based Software for the Integration of Pathway Data into Bioinformatic Algorithms" @default.
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- W2023237744 doi "https://doi.org/10.3390/biology3010085" @default.
- W2023237744 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4009765" @default.
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