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- W2023242112 abstract "The effect of the myo ‐inositol 1,4,5‐trisphosphate (IP 3 ) analogue, myo ‐inositol 1,4,5‐trisphosphorothioate (IPS 3 ) on the dephosphorylation of D‐5‐[ 32 P]IP 3 by the 5‐phosphatase from human erythrocyte membranes has been investigated. DL‐IPS 3 was found to act as a competitive inhibitor with a K i of 6 μM, making it the most potent inhibitor currently available for this enzyme. L‐IP 3 inhibited the enzyme with a K i of 124 μM and was more potent than D‐2,3‐diphosphoglycerate ( K i 978 μM)." @default.
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- W2023242112 date "1989-01-02" @default.
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- W2023242112 title "<i>myo</i> -Inositol 1,4,5-trisphosphorothioate is a potent competitive inhibitor of human erythrocyte 5-phosphatase" @default.
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- W2023242112 doi "https://doi.org/10.1016/0014-5793(89)80504-6" @default.
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