FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023243722> ?p ?o ?g. }

• W2023243722 endingPage "26" @default.
• W2023243722 startingPage "23" @default.
• W2023243722 abstract "Renal prostaglandins, particularly PGE(2), play a homeostatic role in the immature kidney through their hemodynamic and tubular effects, and this role may be crucial under conditions of renal stress. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in the neonatal period to treat or prevent patent ductus arteriosus (PDA) in preterm infants. The nephrotoxic effects induced by NSAIDs result from the inhibition of renal cyclooxygenase activity and prostaglandin synthesis. NSAID-induced prostaglandin inhibition may result in renal hypoperfusion and acute renal failure which are clinically relevant, but usually reversible, adverse effects in the newborn. Currently, ibuprofen appears to be the therapeutic option of choice in the preterm newborn with PDA because of its better renal tolerability compared to other NSAIDs. Nevertheless, the use of this drug is not free from adverse renal effects, particularly in circumstances when renal prostaglandin activation is maximal. The implementation of measures to prevent or minimise nephrotoxicity and close monitoring of renal function are mandatory in the newborn treated with NSAIDs. The measurement of urinary PGE(2) may represent a non-invasive and sensitive tool to evaluate renal function, and thus should be implemented in the clinical management of newborns exposed to nephrotoxic insults." @default.
• W2023243722 created "2016-06-24" @default.
• W2023243722 creator A5012181482 @default.
• W2023243722 creator A5090835076 @default.
• W2023243722 date "2009-01-01" @default.
• W2023243722 modified "2023-09-26" @default.
• W2023243722 title "NSAIDs, prostaglandins and the neonatal kidney" @default.
• W2023243722 cites W1966418337 @default.
• W2023243722 cites W1972658399 @default.
• W2023243722 cites W1976128127 @default.
• W2023243722 cites W1987980917 @default.
• W2023243722 cites W1988090876 @default.
• W2023243722 cites W1990427380 @default.
• W2023243722 cites W1996203912 @default.
• W2023243722 cites W2013186332 @default.
• W2023243722 cites W2016551262 @default.
• W2023243722 cites W2021713115 @default.
• W2023243722 cites W2022931055 @default.
• W2023243722 cites W2034986768 @default.
• W2023243722 cites W2070855421 @default.
• W2023243722 cites W2083939616 @default.
• W2023243722 cites W2085040402 @default.
• W2023243722 cites W2088679350 @default.
• W2023243722 cites W2095286983 @default.
• W2023243722 cites W2121612337 @default.
• W2023243722 cites W2169199617 @default.
• W2023243722 cites W2169477554 @default.
• W2023243722 cites W2312652235 @default.
• W2023243722 cites W2334157623 @default.
• W2023243722 doi "https://doi.org/10.1080/14767050903184447" @default.
• W2023243722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19701861" @default.
• W2023243722 hasPublicationYear "2009" @default.
• W2023243722 type Work @default.
• W2023243722 sameAs 2023243722 @default.
• W2023243722 citedByCount "19" @default.
• W2023243722 countsByYear W20232437222012 @default.
• W2023243722 countsByYear W20232437222014 @default.
• W2023243722 countsByYear W20232437222015 @default.
• W2023243722 countsByYear W20232437222016 @default.
• W2023243722 countsByYear W20232437222018 @default.
• W2023243722 countsByYear W20232437222019 @default.
• W2023243722 countsByYear W20232437222020 @default.
• W2023243722 countsByYear W20232437222021 @default.
• W2023243722 countsByYear W20232437222022 @default.
• W2023243722 countsByYear W20232437222023 @default.
• W2023243722 crossrefType "journal-article" @default.
• W2023243722 hasAuthorship W2023243722A5012181482 @default.
• W2023243722 hasAuthorship W2023243722A5090835076 @default.
• W2023243722 hasConcept C126189478 @default.
• W2023243722 hasConcept C126322002 @default.
• W2023243722 hasConcept C126894567 @default.
• W2023243722 hasConcept C159641895 @default.
• W2023243722 hasConcept C181199279 @default.
• W2023243722 hasConcept C185592680 @default.
• W2023243722 hasConcept C197934379 @default.
• W2023243722 hasConcept C2778375690 @default.
• W2023243722 hasConcept C2779689624 @default.
• W2023243722 hasConcept C2779944601 @default.
• W2023243722 hasConcept C2780091579 @default.
• W2023243722 hasConcept C2780664492 @default.
• W2023243722 hasConcept C2781236024 @default.
• W2023243722 hasConcept C55493867 @default.
• W2023243722 hasConcept C71924100 @default.
• W2023243722 hasConcept C77411442 @default.
• W2023243722 hasConcept C98274493 @default.
• W2023243722 hasConceptScore W2023243722C126189478 @default.
• W2023243722 hasConceptScore W2023243722C126322002 @default.
• W2023243722 hasConceptScore W2023243722C126894567 @default.
• W2023243722 hasConceptScore W2023243722C159641895 @default.
• W2023243722 hasConceptScore W2023243722C181199279 @default.
• W2023243722 hasConceptScore W2023243722C185592680 @default.
• W2023243722 hasConceptScore W2023243722C197934379 @default.
• W2023243722 hasConceptScore W2023243722C2778375690 @default.
• W2023243722 hasConceptScore W2023243722C2779689624 @default.
• W2023243722 hasConceptScore W2023243722C2779944601 @default.
• W2023243722 hasConceptScore W2023243722C2780091579 @default.
• W2023243722 hasConceptScore W2023243722C2780664492 @default.
• W2023243722 hasConceptScore W2023243722C2781236024 @default.
• W2023243722 hasConceptScore W2023243722C55493867 @default.
• W2023243722 hasConceptScore W2023243722C71924100 @default.
• W2023243722 hasConceptScore W2023243722C77411442 @default.
• W2023243722 hasConceptScore W2023243722C98274493 @default.
• W2023243722 hasIssue "sup3" @default.
• W2023243722 hasLocation W20232437221 @default.
• W2023243722 hasLocation W20232437222 @default.
• W2023243722 hasOpenAccess W2023243722 @default.
• W2023243722 hasPrimaryLocation W20232437221 @default.
• W2023243722 hasRelatedWork W143333192 @default.
• W2023243722 hasRelatedWork W1575876011 @default.
• W2023243722 hasRelatedWork W1980466497 @default.
• W2023243722 hasRelatedWork W1982105896 @default.
• W2023243722 hasRelatedWork W2019370793 @default.
• W2023243722 hasRelatedWork W2021839451 @default.
• W2023243722 hasRelatedWork W2058895567 @default.
• W2023243722 hasRelatedWork W2322146251 @default.
• W2023243722 hasRelatedWork W3199424184 @default.
• W2023243722 hasRelatedWork W70079486 @default.
• W2023243722 hasVolume "22" @default.

• next