FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023244761> ?p ?o ?g. }

• W2023244761 endingPage "671" @default.
• W2023244761 startingPage "665" @default.
• W2023244761 abstract "SpoIIGA is a novel type of membrane-associated aspartic protease that responds to a signal from the forespore by cleaving Pro-σ(E) in the mother cell during sporulation of Bacillus subtilis. Very little is known about how SpoIIGA recognizes Pro-σ(E). By co-expressing proteins in Escherichia coli, it was shown that charge reversal substitutions for acidic residues 24 and 25 of Pro-σ(E), and for basic residues 245 and 284 of SpoIIGA, impaired cleavage. These results are consistent with a model predicting possible electrostatic interactions between these residues; however, no charge reversal substitution for residue 245 or residue 284 of SpoIIGA restored cleavage of Pro-σ(E) with a charge reversal substitution for residue 24 or residue 25. Bacillus subtilis SpoIIGA cleaved Pro-σ(E) orthologs from Bacillus licheniformis and Bacillus halodurans, but not from Bacillus cereus. A triple substitution in the pro-sequence of B. cereus Pro-σ(E) allowed cleavage by B. subtilis SpoIIGA, indicating that residues distal from the cleavage site contribute to substrate specificity. Co-expression of SpoIIGA and Pro-σ(E) orthologs in different combinations suggested that B. licheniformis SpoIIGA has a relatively narrow substrate specificity as compared with B. subtilis SpoIIGA, whereas B. cereus SpoIIGA and B. halodurans SpoIIGA appear to have broader substrate specificity." @default.
• W2023244761 created "2016-06-24" @default.
• W2023244761 creator A5029058960 @default.
• W2023244761 creator A5036029498 @default.
• W2023244761 creator A5040744686 @default.
• W2023244761 creator A5055795900 @default.
• W2023244761 creator A5061800523 @default.
• W2023244761 creator A5091887194 @default.
• W2023244761 date "2011-02-28" @default.
• W2023244761 modified "2023-10-14" @default.
• W2023244761 title "Substrate specificity of SpoIIGA, a signal-transducing aspartic protease in Bacilli" @default.
• W2023244761 cites W1490726523 @default.
• W2023244761 cites W1539601278 @default.
• W2023244761 cites W1543653860 @default.
• W2023244761 cites W1597078147 @default.
• W2023244761 cites W1673520687 @default.
• W2023244761 cites W2007130448 @default.
• W2023244761 cites W2007631320 @default.
• W2023244761 cites W2007839457 @default.
• W2023244761 cites W2021606207 @default.
• W2023244761 cites W2030065348 @default.
• W2023244761 cites W2037803546 @default.
• W2023244761 cites W2046391028 @default.
• W2023244761 cites W2053149333 @default.
• W2023244761 cites W2066666929 @default.
• W2023244761 cites W2089433978 @default.
• W2023244761 cites W2100889355 @default.
• W2023244761 cites W2101436427 @default.
• W2023244761 cites W2125766807 @default.
• W2023244761 cites W2131672676 @default.
• W2023244761 cites W2137015675 @default.
• W2023244761 cites W2156860336 @default.
• W2023244761 cites W2163928879 @default.
• W2023244761 cites W2169621668 @default.
• W2023244761 doi "https://doi.org/10.1093/jb/mvr027" @default.
• W2023244761 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3143438" @default.
• W2023244761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21362630" @default.
• W2023244761 hasPublicationYear "2011" @default.
• W2023244761 type Work @default.
• W2023244761 sameAs 2023244761 @default.
• W2023244761 citedByCount "7" @default.
• W2023244761 countsByYear W20232447612012 @default.
• W2023244761 countsByYear W20232447612013 @default.
• W2023244761 countsByYear W20232447612014 @default.
• W2023244761 countsByYear W20232447612019 @default.
• W2023244761 countsByYear W20232447612023 @default.
• W2023244761 crossrefType "journal-article" @default.
• W2023244761 hasAuthorship W2023244761A5029058960 @default.
• W2023244761 hasAuthorship W2023244761A5036029498 @default.
• W2023244761 hasAuthorship W2023244761A5040744686 @default.
• W2023244761 hasAuthorship W2023244761A5055795900 @default.
• W2023244761 hasAuthorship W2023244761A5061800523 @default.
• W2023244761 hasAuthorship W2023244761A5091887194 @default.
• W2023244761 hasBestOaLocation W20232447612 @default.
• W2023244761 hasConcept C104317684 @default.
• W2023244761 hasConcept C10858879 @default.
• W2023244761 hasConcept C151730666 @default.
• W2023244761 hasConcept C167625842 @default.
• W2023244761 hasConcept C175156509 @default.
• W2023244761 hasConcept C181199279 @default.
• W2023244761 hasConcept C185592680 @default.
• W2023244761 hasConcept C2776527165 @default.
• W2023244761 hasConcept C2776714187 @default.
• W2023244761 hasConcept C2777118263 @default.
• W2023244761 hasConcept C2777272437 @default.
• W2023244761 hasConcept C2777932965 @default.
• W2023244761 hasConcept C2778039104 @default.
• W2023244761 hasConcept C2779190341 @default.
• W2023244761 hasConcept C2780373777 @default.
• W2023244761 hasConcept C2781338088 @default.
• W2023244761 hasConcept C43369102 @default.
• W2023244761 hasConcept C523546767 @default.
• W2023244761 hasConcept C54355233 @default.
• W2023244761 hasConcept C547475151 @default.
• W2023244761 hasConcept C55493867 @default.
• W2023244761 hasConcept C71240020 @default.
• W2023244761 hasConcept C86803240 @default.
• W2023244761 hasConceptScore W2023244761C104317684 @default.
• W2023244761 hasConceptScore W2023244761C10858879 @default.
• W2023244761 hasConceptScore W2023244761C151730666 @default.
• W2023244761 hasConceptScore W2023244761C167625842 @default.
• W2023244761 hasConceptScore W2023244761C175156509 @default.
• W2023244761 hasConceptScore W2023244761C181199279 @default.
• W2023244761 hasConceptScore W2023244761C185592680 @default.
• W2023244761 hasConceptScore W2023244761C2776527165 @default.
• W2023244761 hasConceptScore W2023244761C2776714187 @default.
• W2023244761 hasConceptScore W2023244761C2777118263 @default.
• W2023244761 hasConceptScore W2023244761C2777272437 @default.
• W2023244761 hasConceptScore W2023244761C2777932965 @default.
• W2023244761 hasConceptScore W2023244761C2778039104 @default.
• W2023244761 hasConceptScore W2023244761C2779190341 @default.
• W2023244761 hasConceptScore W2023244761C2780373777 @default.
• W2023244761 hasConceptScore W2023244761C2781338088 @default.
• W2023244761 hasConceptScore W2023244761C43369102 @default.
• W2023244761 hasConceptScore W2023244761C523546767 @default.
• W2023244761 hasConceptScore W2023244761C54355233 @default.
• W2023244761 hasConceptScore W2023244761C547475151 @default.
• W2023244761 hasConceptScore W2023244761C55493867 @default.

• next