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• W2023246619 startingPage "10104" @default.
• W2023246619 abstract "We report that tumor necrosis factor alpha (TNF-alpha) mRNA is increased after treatment with x-rays in certain human sarcoma cells. An increase in TNF-alpha mRNA is accompanied by the increased production of TNF-alpha protein. TNF-alpha enhances radiation lethality in both TNF-alpha-producing and -nonproducing tumor cells. These data suggest that, in addition to the direct cytotoxic effects of x-rays, production of TNF-alpha may add to radiation lethality through autocrine and paracrine mechanisms. Combinations of TNF-alpha and therapeutic radiation may be useful in clinical cancer therapy." @default.
• W2023246619 created "2016-06-24" @default.
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• W2023246619 date "1989-12-01" @default.
• W2023246619 modified "2023-10-17" @default.
• W2023246619 title "Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation." @default.
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• W2023246619 doi "https://doi.org/10.1073/pnas.86.24.10104" @default.
• W2023246619 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/298653" @default.
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