FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023247467> ?p ?o ?g. }

• W2023247467 endingPage "38" @default.
• W2023247467 startingPage "30" @default.
• W2023247467 abstract "Recent work carried out in our laboratory showed the existence of a cytokine storm in SARS patients, dominated by Th1-type mediators. We thus hypothesized that IFN-gamma may play a major role in the pathology by triggering immune-mediated alveolar damage. As we assessed or re-assessed some effects of IFN-gamma on a number of human lung epithelial and fibroblast cell lines, chosen for their wide use in the literature, we found that alveolar epithelial cells were more sensitive to IFN-gamma, in terms of proliferation inhibition and enhancement of Fas-mediated apoptosis. While similar effects were obtained on fibroblasts, concentrations of IFN-gamma 4--8-fold greater were required. In addition, both epithelial and fibroblastic cell lines were able to secrete large quantities of T cell-targeting chemokines, similar to the ones detected in SARS patients. Based on the clinical data collected previously, the available literature and our in vitro experimentation, we propose that IFN-gamma may be responsible for acute lung injury in the late phase of the SARS pathology." @default.
• W2023247467 created "2016-06-24" @default.
• W2023247467 creator A5028277866 @default.
• W2023247467 creator A5036476165 @default.
• W2023247467 creator A5038177250 @default.
• W2023247467 creator A5047995189 @default.
• W2023247467 creator A5070222189 @default.
• W2023247467 date "2005-10-07" @default.
• W2023247467 modified "2023-10-01" @default.
• W2023247467 title "A probable role for IFN-γ in the development of a lung immunopathology in SARS" @default.
• W2023247467 cites W1560596088 @default.
• W2023247467 cites W1983357763 @default.
• W2023247467 cites W1993924965 @default.
• W2023247467 cites W2003786327 @default.
• W2023247467 cites W2025170735 @default.
• W2023247467 cites W2026879700 @default.
• W2023247467 cites W2038447078 @default.
• W2023247467 cites W2045214007 @default.
• W2023247467 cites W2070463916 @default.
• W2023247467 cites W2075653792 @default.
• W2023247467 cites W2087376270 @default.
• W2023247467 cites W2096092997 @default.
• W2023247467 cites W2103225233 @default.
• W2023247467 cites W2104548316 @default.
• W2023247467 cites W2129542667 @default.
• W2023247467 cites W2132260239 @default.
• W2023247467 cites W2148208988 @default.
• W2023247467 cites W2151125798 @default.
• W2023247467 cites W2151630650 @default.
• W2023247467 cites W2158118659 @default.
• W2023247467 cites W2162809912 @default.
• W2023247467 cites W2163627712 @default.
• W2023247467 cites W2170984368 @default.
• W2023247467 cites W2183859574 @default.
• W2023247467 cites W2229805806 @default.
• W2023247467 cites W34521598 @default.
• W2023247467 cites W50778882 @default.
• W2023247467 doi "https://doi.org/10.1016/j.cyto.2005.07.007" @default.
• W2023247467 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7129778" @default.
• W2023247467 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16129616" @default.
• W2023247467 hasPublicationYear "2005" @default.
• W2023247467 type Work @default.
• W2023247467 sameAs 2023247467 @default.
• W2023247467 citedByCount "54" @default.
• W2023247467 countsByYear W20232474672012 @default.
• W2023247467 countsByYear W20232474672013 @default.
• W2023247467 countsByYear W20232474672014 @default.
• W2023247467 countsByYear W20232474672015 @default.
• W2023247467 countsByYear W20232474672017 @default.
• W2023247467 countsByYear W20232474672020 @default.
• W2023247467 countsByYear W20232474672021 @default.
• W2023247467 countsByYear W20232474672022 @default.
• W2023247467 countsByYear W20232474672023 @default.
• W2023247467 crossrefType "journal-article" @default.
• W2023247467 hasAuthorship W2023247467A5028277866 @default.
• W2023247467 hasAuthorship W2023247467A5036476165 @default.
• W2023247467 hasAuthorship W2023247467A5038177250 @default.
• W2023247467 hasAuthorship W2023247467A5047995189 @default.
• W2023247467 hasAuthorship W2023247467A5070222189 @default.
• W2023247467 hasBestOaLocation W20232474671 @default.
• W2023247467 hasConcept C126322002 @default.
• W2023247467 hasConcept C13373296 @default.
• W2023247467 hasConcept C142724271 @default.
• W2023247467 hasConcept C190283241 @default.
• W2023247467 hasConcept C202751555 @default.
• W2023247467 hasConcept C203014093 @default.
• W2023247467 hasConcept C2777714996 @default.
• W2023247467 hasConcept C2778690821 @default.
• W2023247467 hasConcept C2780381497 @default.
• W2023247467 hasConcept C2780648854 @default.
• W2023247467 hasConcept C2780841837 @default.
• W2023247467 hasConcept C49039625 @default.
• W2023247467 hasConcept C502942594 @default.
• W2023247467 hasConcept C529295009 @default.
• W2023247467 hasConcept C54355233 @default.
• W2023247467 hasConcept C55493867 @default.
• W2023247467 hasConcept C71924100 @default.
• W2023247467 hasConcept C81885089 @default.
• W2023247467 hasConcept C86803240 @default.
• W2023247467 hasConcept C8891405 @default.
• W2023247467 hasConceptScore W2023247467C126322002 @default.
• W2023247467 hasConceptScore W2023247467C13373296 @default.
• W2023247467 hasConceptScore W2023247467C142724271 @default.
• W2023247467 hasConceptScore W2023247467C190283241 @default.
• W2023247467 hasConceptScore W2023247467C202751555 @default.
• W2023247467 hasConceptScore W2023247467C203014093 @default.
• W2023247467 hasConceptScore W2023247467C2777714996 @default.
• W2023247467 hasConceptScore W2023247467C2778690821 @default.
• W2023247467 hasConceptScore W2023247467C2780381497 @default.
• W2023247467 hasConceptScore W2023247467C2780648854 @default.
• W2023247467 hasConceptScore W2023247467C2780841837 @default.
• W2023247467 hasConceptScore W2023247467C49039625 @default.
• W2023247467 hasConceptScore W2023247467C502942594 @default.
• W2023247467 hasConceptScore W2023247467C529295009 @default.
• W2023247467 hasConceptScore W2023247467C54355233 @default.
• W2023247467 hasConceptScore W2023247467C55493867 @default.
• W2023247467 hasConceptScore W2023247467C71924100 @default.
• W2023247467 hasConceptScore W2023247467C81885089 @default.

• next