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- W2023255762 abstract "Insulin secretion by intact islets, dispersed islet cells and dispersed cells allowed to reaggregate was compared in perifusion. Although single cells and aggregates showed basal insulin secretion and a prompt response to glucose challenge, basal secretion, peak insulin secretion and total insulin secretion during a 60 minute stimulation were profoundly less than those activities of intact islets. These results suggest that dispersed beta cells are responsive to glucose as a secretagogue, but the magnitude of the response is greatly diminished and not restored by simple cell contact." @default.
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- W2023255762 date "1988-06-01" @default.
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- W2023255762 title "Beta cell contact and insulin release" @default.
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- W2023255762 doi "https://doi.org/10.1016/s0006-291x(88)81327-5" @default.
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