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• W2023255785 abstract "Melatonin is known as an antistress and immunostimulator compound while glucocorticoids have immunosuppressive function. The mechanism of action of both the hormones on immune cells is still a question. We found that melatonin improved the effect of dexamethasone (synthetic glucocorticoid) induced immunosuppression of splenocytes and bone marrow GM-CFU along with increased production of serum IL-2, IgG and the receptor expression for melatonin and glucocorticoid in spleen that might be responsible for the proliferation of immune cells. Thus, seasonal variation in peripheral melatonin might be responsible for the improvement of immune status under different stress conditions experienced by the rodents for better survival." @default.
• W2023255785 created "2016-06-24" @default.
• W2023255785 creator A5063431599 @default.
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• W2023255785 date "2013-06-01" @default.
• W2023255785 modified "2023-10-17" @default.
• W2023255785 title "Melatonin improves humoral and cell-mediated immune responses of male golden hamster following stress induced by dexamethasone" @default.
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• W2023255785 doi "https://doi.org/10.1016/j.jneuroim.2013.03.002" @default.
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