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• W2023256592 abstract "Immunohistochemical examination demonstrated widespread granular deposits of alpha-synuclein (alphaSN) in the brains of sheep and goats with natural scrapie, especially in the cornu ammonis and subiculum of the hippocampus; this contrasted with the diffuse and non-granular immunolabelling seen in healthy controls. There was non-regular co-localization of PrP(Sc) and alphaSN. The findings resembled those reported in Creutzfeldt-Jakob disease and in experimental prion disease in hamsters and mice. The results suggest that perturbation of alphaSN metabolism plays a role in human and animal prion diseases." @default.
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• W2023256592 date "2007-07-01" @default.
• W2023256592 modified "2023-10-16" @default.
• W2023256592 title "Alpha-synuclein Accumulates in the Brain of Scrapie-affected Sheep and Goats" @default.
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• W2023256592 doi "https://doi.org/10.1016/j.jcpa.2007.03.007" @default.
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