Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023259327> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2023259327 endingPage "373" @default.
- W2023259327 startingPage "369" @default.
- W2023259327 abstract "The effects of ATP and ADP structural analogues (2-methylthio ATP; alpha,beta-methylene ADP) on somatostatin secretion were tested in dogs. Insulin and glucagon secretion was also evaluated. Our experiments were performed in vivo and in vitro. In vivo, 2-methylthio ATP was infused directly into the pancreaticoduodenal artery of anesthetized dogs and blood was sampled from the pancreaticoduodenal vein. This ATP analogue (approximately 15 microM) immediately induced stimulation of both somatostatin and insulin secretion, which was accompanied by a slight reduction of glycemia. A delayed increase in glucagon output was observed. In vitro, using the isolated perfused dog pancreas uncinate process, alpha,beta-methylene ADP, a stable ADP analogue (16.5 microM), was infused in the presence of a substimulating glucose concentration (4.2 mM). Under these conditions, alpha,beta-methylene ADP immediately induced the stimulation of somatostatin secretion without affecting basal insulin and glucagon secretion. In conclusion our results suggest the presence of P2 purinoceptors on pancreatic somatostatin secreting cells." @default.
- W2023259327 created "2016-06-24" @default.
- W2023259327 creator A5016207805 @default.
- W2023259327 creator A5038925073 @default.
- W2023259327 creator A5052874352 @default.
- W2023259327 creator A5057067750 @default.
- W2023259327 date "1990-07-01" @default.
- W2023259327 modified "2023-10-06" @default.
- W2023259327 title "P2 purinoceptor agonists stimulate somatostatin secretion from dog pancreas" @default.
- W2023259327 cites W1980037622 @default.
- W2023259327 cites W1982600820 @default.
- W2023259327 cites W2016578399 @default.
- W2023259327 cites W2027175898 @default.
- W2023259327 cites W2039969300 @default.
- W2023259327 cites W2051081603 @default.
- W2023259327 cites W2056020792 @default.
- W2023259327 cites W2070895240 @default.
- W2023259327 cites W2078073869 @default.
- W2023259327 cites W2146415791 @default.
- W2023259327 cites W2164832987 @default.
- W2023259327 cites W2883434548 @default.
- W2023259327 cites W4236293311 @default.
- W2023259327 cites W4238788279 @default.
- W2023259327 cites W4244858109 @default.
- W2023259327 doi "https://doi.org/10.1016/0014-2999(90)90296-i" @default.
- W2023259327 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1975783" @default.
- W2023259327 hasPublicationYear "1990" @default.
- W2023259327 type Work @default.
- W2023259327 sameAs 2023259327 @default.
- W2023259327 citedByCount "21" @default.
- W2023259327 countsByYear W20232593272012 @default.
- W2023259327 countsByYear W20232593272013 @default.
- W2023259327 countsByYear W20232593272014 @default.
- W2023259327 countsByYear W20232593272015 @default.
- W2023259327 countsByYear W20232593272016 @default.
- W2023259327 countsByYear W20232593272018 @default.
- W2023259327 countsByYear W20232593272019 @default.
- W2023259327 countsByYear W20232593272020 @default.
- W2023259327 crossrefType "journal-article" @default.
- W2023259327 hasAuthorship W2023259327A5016207805 @default.
- W2023259327 hasAuthorship W2023259327A5038925073 @default.
- W2023259327 hasAuthorship W2023259327A5052874352 @default.
- W2023259327 hasAuthorship W2023259327A5057067750 @default.
- W2023259327 hasConcept C126322002 @default.
- W2023259327 hasConcept C134018914 @default.
- W2023259327 hasConcept C150903083 @default.
- W2023259327 hasConcept C185592680 @default.
- W2023259327 hasConcept C207001950 @default.
- W2023259327 hasConcept C24998067 @default.
- W2023259327 hasConcept C2776297358 @default.
- W2023259327 hasConcept C2776991684 @default.
- W2023259327 hasConcept C2778563252 @default.
- W2023259327 hasConcept C2778764654 @default.
- W2023259327 hasConcept C2779306644 @default.
- W2023259327 hasConcept C49039625 @default.
- W2023259327 hasConcept C57306754 @default.
- W2023259327 hasConcept C71924100 @default.
- W2023259327 hasConcept C86803240 @default.
- W2023259327 hasConceptScore W2023259327C126322002 @default.
- W2023259327 hasConceptScore W2023259327C134018914 @default.
- W2023259327 hasConceptScore W2023259327C150903083 @default.
- W2023259327 hasConceptScore W2023259327C185592680 @default.
- W2023259327 hasConceptScore W2023259327C207001950 @default.
- W2023259327 hasConceptScore W2023259327C24998067 @default.
- W2023259327 hasConceptScore W2023259327C2776297358 @default.
- W2023259327 hasConceptScore W2023259327C2776991684 @default.
- W2023259327 hasConceptScore W2023259327C2778563252 @default.
- W2023259327 hasConceptScore W2023259327C2778764654 @default.
- W2023259327 hasConceptScore W2023259327C2779306644 @default.
- W2023259327 hasConceptScore W2023259327C49039625 @default.
- W2023259327 hasConceptScore W2023259327C57306754 @default.
- W2023259327 hasConceptScore W2023259327C71924100 @default.
- W2023259327 hasConceptScore W2023259327C86803240 @default.
- W2023259327 hasIssue "2" @default.
- W2023259327 hasLocation W20232593271 @default.
- W2023259327 hasLocation W20232593272 @default.
- W2023259327 hasOpenAccess W2023259327 @default.
- W2023259327 hasPrimaryLocation W20232593271 @default.
- W2023259327 hasRelatedWork W1970189861 @default.
- W2023259327 hasRelatedWork W1992143981 @default.
- W2023259327 hasRelatedWork W1992958920 @default.
- W2023259327 hasRelatedWork W1995945960 @default.
- W2023259327 hasRelatedWork W2017797235 @default.
- W2023259327 hasRelatedWork W2070076315 @default.
- W2023259327 hasRelatedWork W2074580268 @default.
- W2023259327 hasRelatedWork W2081409127 @default.
- W2023259327 hasRelatedWork W2085559395 @default.
- W2023259327 hasRelatedWork W2146169475 @default.
- W2023259327 hasVolume "182" @default.
- W2023259327 isParatext "false" @default.
- W2023259327 isRetracted "false" @default.
- W2023259327 magId "2023259327" @default.
- W2023259327 workType "article" @default.