Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023261936> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2023261936 endingPage "391" @default.
- W2023261936 startingPage "383" @default.
- W2023261936 abstract "The study presents an accurate and precise HPLC assay for the determination of furosemide and amiloride in human specimens. Both drugs were extracted from human plasma with ethyl acetate; furosemide was extracted at pH 1 and amiloride at pH 12. While chromatographic separation conditions, i.e., column, mobile phase and flow-rate were the same for both investigated drugs, furosemide was detected using a UV absorbance detector, whereas amiloride, because of its very low therapeutic range, was detected with a spectrofluorimetric detector. The linearity of the furosemide and amiloride assays were confirmed over the range of 30-3000 ng/ml and 0.5-30 ng/ml, respectively. These concentrations correspond well with the therapeutic ranges of both drugs. The extraction recoveries, depending on concentration, exceed 80% for furosemide and 74% for amiloride. The reported methods were applied to pharmacokinetic investigations of the two compounds taken in form of a drug combination." @default.
- W2023261936 created "2016-06-24" @default.
- W2023261936 creator A5010363769 @default.
- W2023261936 creator A5023830316 @default.
- W2023261936 creator A5040839694 @default.
- W2023261936 date "1997-06-01" @default.
- W2023261936 modified "2023-09-27" @default.
- W2023261936 title "Determination and pharmacokinetics of a furosemide–amiloride drug combination" @default.
- W2023261936 cites W1793032515 @default.
- W2023261936 cites W1979634507 @default.
- W2023261936 cites W1985320205 @default.
- W2023261936 cites W2027347284 @default.
- W2023261936 cites W2047602212 @default.
- W2023261936 cites W2057151261 @default.
- W2023261936 cites W2088865843 @default.
- W2023261936 cites W2115845874 @default.
- W2023261936 cites W2117207945 @default.
- W2023261936 cites W2133277789 @default.
- W2023261936 cites W2137112875 @default.
- W2023261936 cites W2155223429 @default.
- W2023261936 cites W4320577855 @default.
- W2023261936 doi "https://doi.org/10.1016/s0378-4347(97)00055-8" @default.
- W2023261936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9210443" @default.
- W2023261936 hasPublicationYear "1997" @default.
- W2023261936 type Work @default.
- W2023261936 sameAs 2023261936 @default.
- W2023261936 citedByCount "26" @default.
- W2023261936 countsByYear W20232619362012 @default.
- W2023261936 countsByYear W20232619362013 @default.
- W2023261936 countsByYear W20232619362014 @default.
- W2023261936 countsByYear W20232619362015 @default.
- W2023261936 countsByYear W20232619362016 @default.
- W2023261936 countsByYear W20232619362017 @default.
- W2023261936 countsByYear W20232619362019 @default.
- W2023261936 countsByYear W20232619362020 @default.
- W2023261936 crossrefType "journal-article" @default.
- W2023261936 hasAuthorship W2023261936A5010363769 @default.
- W2023261936 hasAuthorship W2023261936A5023830316 @default.
- W2023261936 hasAuthorship W2023261936A5040839694 @default.
- W2023261936 hasConcept C112705442 @default.
- W2023261936 hasConcept C178790620 @default.
- W2023261936 hasConcept C179998833 @default.
- W2023261936 hasConcept C185592680 @default.
- W2023261936 hasConcept C2777955127 @default.
- W2023261936 hasConcept C2779608910 @default.
- W2023261936 hasConcept C2779918671 @default.
- W2023261936 hasConcept C43617362 @default.
- W2023261936 hasConcept C4725764 @default.
- W2023261936 hasConcept C537181965 @default.
- W2023261936 hasConcept C71924100 @default.
- W2023261936 hasConcept C98274493 @default.
- W2023261936 hasConceptScore W2023261936C112705442 @default.
- W2023261936 hasConceptScore W2023261936C178790620 @default.
- W2023261936 hasConceptScore W2023261936C179998833 @default.
- W2023261936 hasConceptScore W2023261936C185592680 @default.
- W2023261936 hasConceptScore W2023261936C2777955127 @default.
- W2023261936 hasConceptScore W2023261936C2779608910 @default.
- W2023261936 hasConceptScore W2023261936C2779918671 @default.
- W2023261936 hasConceptScore W2023261936C43617362 @default.
- W2023261936 hasConceptScore W2023261936C4725764 @default.
- W2023261936 hasConceptScore W2023261936C537181965 @default.
- W2023261936 hasConceptScore W2023261936C71924100 @default.
- W2023261936 hasConceptScore W2023261936C98274493 @default.
- W2023261936 hasIssue "2" @default.
- W2023261936 hasLocation W20232619361 @default.
- W2023261936 hasLocation W20232619362 @default.
- W2023261936 hasOpenAccess W2023261936 @default.
- W2023261936 hasPrimaryLocation W20232619361 @default.
- W2023261936 hasRelatedWork W1975289039 @default.
- W2023261936 hasRelatedWork W2070170242 @default.
- W2023261936 hasRelatedWork W2074499292 @default.
- W2023261936 hasRelatedWork W2090660144 @default.
- W2023261936 hasRelatedWork W2147381230 @default.
- W2023261936 hasRelatedWork W2395066389 @default.
- W2023261936 hasRelatedWork W2408155025 @default.
- W2023261936 hasRelatedWork W2409027245 @default.
- W2023261936 hasRelatedWork W2410349162 @default.
- W2023261936 hasRelatedWork W2413642610 @default.
- W2023261936 hasVolume "693" @default.
- W2023261936 isParatext "false" @default.
- W2023261936 isRetracted "false" @default.
- W2023261936 magId "2023261936" @default.
- W2023261936 workType "article" @default.