Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023271694> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2023271694 endingPage "125" @default.
- W2023271694 startingPage "120" @default.
- W2023271694 abstract "Compared with healthy individuals, patients with chronic liver disease reportedly have lower L-[1-13C] phenylalanine breath test (PBT) values. However, there is no report detailing the relationship between the results of PBT and pathological data in liver disease patients. This study was designed to investigate the degree of histological changes in the liver that induce PBT changes and the time of measurement that reflects the histological change.PBT was performed in 47 patients (10 with a normal liver, and 37 with chronic hepatitis C). After administering 10 mg/kg L-[1-13C] phenylalanine, 300 mL of expired air was collected over 90 min at 15-min intervals. The rate of hepatic phenylalanine oxidation (%13C dose h(-1)) at each time point was calculated from the amount of 13CO(2) in the exhaled air, assuming a CO(2) production rate of 300 mmol m(-2) body surface area per hour. Subsequently, we examined the relationship between the results of PBT and METAVIR pathological scoring.The highest correlation coefficients between the fibrosis score and %13C dose h(-1) and between the fibrosis score and %13C cumulative excretion were obtained at 45 min (r = -0.779, R(2) = 0.607; P < 0.0001) and 75 min (r = -0.768, R(2) = 0.590; P < 0.0001), respectively.PBT is a useful adjunct for detecting histological changes in the liver. The %13C dose h(-1) value at 45 min and the %13C cumulative excretion value at 75 min of PBT are useful for detecting hepatic histological change." @default.
- W2023271694 created "2016-06-24" @default.
- W2023271694 creator A5040477628 @default.
- W2023271694 creator A5040778839 @default.
- W2023271694 creator A5041567002 @default.
- W2023271694 creator A5059523458 @default.
- W2023271694 creator A5059623734 @default.
- W2023271694 creator A5069502632 @default.
- W2023271694 creator A5087459078 @default.
- W2023271694 date "2003-10-01" @default.
- W2023271694 modified "2023-10-15" @default.
- W2023271694 title "L-[1- 13 C] phenylalanine breath test reflects histological changes in the liver" @default.
- W2023271694 cites W1574726974 @default.
- W2023271694 cites W1962437641 @default.
- W2023271694 cites W1976021080 @default.
- W2023271694 cites W1991749558 @default.
- W2023271694 cites W1994851922 @default.
- W2023271694 cites W2042536749 @default.
- W2023271694 cites W2058515064 @default.
- W2023271694 cites W2063051677 @default.
- W2023271694 cites W2073407581 @default.
- W2023271694 cites W2104832151 @default.
- W2023271694 cites W2114376411 @default.
- W2023271694 cites W2135410177 @default.
- W2023271694 cites W2138391231 @default.
- W2023271694 cites W2153940185 @default.
- W2023271694 cites W2160297030 @default.
- W2023271694 doi "https://doi.org/10.1016/s0022-4804(03)00278-6" @default.
- W2023271694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14559436" @default.
- W2023271694 hasPublicationYear "2003" @default.
- W2023271694 type Work @default.
- W2023271694 sameAs 2023271694 @default.
- W2023271694 citedByCount "22" @default.
- W2023271694 countsByYear W20232716942012 @default.
- W2023271694 countsByYear W20232716942013 @default.
- W2023271694 countsByYear W20232716942016 @default.
- W2023271694 countsByYear W20232716942020 @default.
- W2023271694 crossrefType "journal-article" @default.
- W2023271694 hasAuthorship W2023271694A5040477628 @default.
- W2023271694 hasAuthorship W2023271694A5040778839 @default.
- W2023271694 hasAuthorship W2023271694A5041567002 @default.
- W2023271694 hasAuthorship W2023271694A5059523458 @default.
- W2023271694 hasAuthorship W2023271694A5059623734 @default.
- W2023271694 hasAuthorship W2023271694A5069502632 @default.
- W2023271694 hasAuthorship W2023271694A5087459078 @default.
- W2023271694 hasConcept C10146269 @default.
- W2023271694 hasConcept C126322002 @default.
- W2023271694 hasConcept C142724271 @default.
- W2023271694 hasConcept C185592680 @default.
- W2023271694 hasConcept C207886595 @default.
- W2023271694 hasConcept C2775981797 @default.
- W2023271694 hasConcept C2776409635 @default.
- W2023271694 hasConcept C2777075537 @default.
- W2023271694 hasConcept C2777431362 @default.
- W2023271694 hasConcept C3019162307 @default.
- W2023271694 hasConcept C515207424 @default.
- W2023271694 hasConcept C55493867 @default.
- W2023271694 hasConcept C71924100 @default.
- W2023271694 hasConcept C90924648 @default.
- W2023271694 hasConceptScore W2023271694C10146269 @default.
- W2023271694 hasConceptScore W2023271694C126322002 @default.
- W2023271694 hasConceptScore W2023271694C142724271 @default.
- W2023271694 hasConceptScore W2023271694C185592680 @default.
- W2023271694 hasConceptScore W2023271694C207886595 @default.
- W2023271694 hasConceptScore W2023271694C2775981797 @default.
- W2023271694 hasConceptScore W2023271694C2776409635 @default.
- W2023271694 hasConceptScore W2023271694C2777075537 @default.
- W2023271694 hasConceptScore W2023271694C2777431362 @default.
- W2023271694 hasConceptScore W2023271694C3019162307 @default.
- W2023271694 hasConceptScore W2023271694C515207424 @default.
- W2023271694 hasConceptScore W2023271694C55493867 @default.
- W2023271694 hasConceptScore W2023271694C71924100 @default.
- W2023271694 hasConceptScore W2023271694C90924648 @default.
- W2023271694 hasIssue "2" @default.
- W2023271694 hasLocation W20232716941 @default.
- W2023271694 hasLocation W20232716942 @default.
- W2023271694 hasOpenAccess W2023271694 @default.
- W2023271694 hasPrimaryLocation W20232716941 @default.
- W2023271694 hasRelatedWork W1978251300 @default.
- W2023271694 hasRelatedWork W1984928445 @default.
- W2023271694 hasRelatedWork W1995853007 @default.
- W2023271694 hasRelatedWork W2033750168 @default.
- W2023271694 hasRelatedWork W2069221332 @default.
- W2023271694 hasRelatedWork W2108757169 @default.
- W2023271694 hasRelatedWork W2318345443 @default.
- W2023271694 hasRelatedWork W2412635623 @default.
- W2023271694 hasRelatedWork W4308834494 @default.
- W2023271694 hasRelatedWork W46234838 @default.
- W2023271694 hasVolume "114" @default.
- W2023271694 isParatext "false" @default.
- W2023271694 isRetracted "false" @default.
- W2023271694 magId "2023271694" @default.
- W2023271694 workType "article" @default.