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- W2023271834 abstract "Ribonucleic acid reacts in vitro with basic dyes such as toluidine blue, acridine orange, and pyronine to provoke a shift in the absorption maximum of the dye, either toward a longer (negative metachromasy) or shorter wavelength (positive metachromasy). The direction of the metachromatic shift is dependent on both the relative concentration of the polymer to the dye and on the secondary structure and the chainlength of the polymer. In studies with synthetic polymers, RNA, and RNA-fractions, at known polymer-dye ratios, it was found that the length of the polymer chain determined the extent of positive metachromasy. On the other hand, negative metachromasy appears dependent on density of double-stranded regions in RNA molecules." @default.
- W2023271834 created "2016-06-24" @default.
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- W2023271834 date "1964-10-01" @default.
- W2023271834 modified "2023-09-23" @default.
- W2023271834 title "The interaction of basic dyes with ribonucleic acid" @default.
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- W2023271834 doi "https://doi.org/10.1016/0003-9861(64)90367-4" @default.
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