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- W2023274429 abstract "Chromosome analysis was performed in 17 children ith IgA-deficiency. In two patients a constitutional structural chromosome abnormality was found. A ring chromosome 22 was seen in one, while in the other a mosaicism of ring chromosome 18/18p+ was observed. Both patients wcre metanlly retarded and showed distinct congénital defects. From ten asymptomatic patients, spontaneous as well as X-ray-induced chromosome instability was investigated. There was no increased spontaneous instability, and also after irradiation the induced chromosome damage was within normal control levels. A relationship between IgA-deficiency and X-ray hypersensitivity, as might be suggested by the frequently occurring coïncidence of radiosensitivi-ty and IgA-deficiency in ataxia teleangiectasia patients, is not established." @default.
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- W2023274429 date "2008-06-28" @default.
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- W2023274429 title "Chromosome studies in IgA-deficient patients" @default.
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- W2023274429 doi "https://doi.org/10.1111/j.1399-0004.1987.tb03330.x" @default.
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