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- W2023277714 abstract "Peripheral blood lymphocytes from 23 patients with cutaneous T-cell lymphoma were studied using monoclonal anti-human T-cell antibodies. In nine cases of Sezary syndrome (SS) there was a major expansion of T-lymphocyte subpopulation binding the OKT4 antibody (which recognizes T cells with helper and inducer functions) and a decrease in the percentage of lymphocytes reacting with OKT8 antibody (which binds to suppressor and/or cytotoxic T cells). In 14 cases of MF, a similar but less pronounced T-cell imbalance was found. These data provide direct evidence that like SS, mycosis fungoides (MF) probably represents a helper T-cell neoplasm." @default.
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- W2023277714 date "1981-08-01" @default.
- W2023277714 modified "2023-09-25" @default.
- W2023277714 title "T cell imbalance in nonleukemic and leukemic cutaneous lymphoma defined by monoclonal antibodies" @default.
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- W2023277714 doi "https://doi.org/10.1016/0090-1229(81)90186-0" @default.
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