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• W2023280816 abstract "Clionamine B (2), an aminosteroid isolated from the marine sponge Cliona celata, has been synthesized starting from the plant sapogenin tigogenin (5). A key step in the synsthesis is the stereoselective introduction of the C-20 α-hydroxyl substituent via oxidation of a γ-lactone enolate with molecular oxygen. Synthetic clionamine B (2) strongly stimulated autophagy in human breast cancer MCF-7 cells." @default.
• W2023280816 created "2016-06-24" @default.
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• W2023280816 date "2013-07-19" @default.
• W2023280816 modified "2023-09-25" @default.
• W2023280816 title "Synthesis of Clionamine B, an Autophagy Stimulating Aminosteroid Isolated from the Sponge <i>Cliona celata</i>" @default.
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• W2023280816 doi "https://doi.org/10.1021/ol4016783" @default.
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