FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023282441> ?p ?o ?g. }

• W2023282441 endingPage "e0116004" @default.
• W2023282441 startingPage "e0116004" @default.
• W2023282441 abstract "The aim of this study was to analyze the expression of three metallothionein (MT) isoform genes (CdMT, CuMT and Cd/CuMT), already known from adults, in the Early Life Stage (ELS) of Cantareus aspersus. This was accomplished by detection of the MT isoform-specific transcription adopting Polymerase Chain Reaction (PCR) amplification and quantitative Real Time (qRT)-PCR of the three MT genes. Freshly laid eggs were kept for 24 hours under control conditions or exposed to three cadmium (Cd) solutions of increasing concentration (5, 10, and 15 mg Cd/L). The transcription of the three MT isoform genes was detected via PCR in 1, 6 and 12-day-old control or Cd-exposed embryos. Moreover, the transcription of this isoform genes during development was followed by qRT-PCR in 6 and 12-day-old embryos. Our results showed that the CdMT and Cd/CuMT genes, but not the CuMT gene, are expressed in embryos at the first day of development. The transcription of the 3 MT genes in control embryos increased with development time, suggesting that the capacities of metal regulation and detoxification may have gradually increased throughout embryogenesis. However in control embryos, the most highly expressed MT gene was that of the Cd/CuMT isoform, whose transcription levels greatly exceeded those of the other two MT genes. This contrasts with the minor significance of this gene in adult snails and suggests that in embryos, this isoform may play a comparatively more important role in metal physiology compared to adult individuals. This function in adult snails appears not to be related to Cd detoxification. Instead, snail embryos responded to Cd exposure by over-expression of the CdMT gene in a concentration-dependent manner, whereas the expression of the Cd/CuMT gene remained unaffected. Moreover, our study demonstrates the ability of snail embryos to respond very early to Cd exposure by up-regulation of the CdMT gene." @default.
• W2023282441 created "2016-06-24" @default.
• W2023282441 creator A5001182395 @default.
• W2023282441 creator A5010450792 @default.
• W2023282441 creator A5012028701 @default.
• W2023282441 creator A5047700658 @default.
• W2023282441 creator A5059792777 @default.
• W2023282441 creator A5082653476 @default.
• W2023282441 creator A5091545614 @default.
• W2023282441 date "2015-02-23" @default.
• W2023282441 modified "2023-10-02" @default.
• W2023282441 title "Differential Expression of Metallothionein Isoforms in Terrestrial Snail Embryos Reflects Early Life Stage Adaptation to Metal Stress" @default.
• W2023282441 cites W1495265866 @default.
• W2023282441 cites W1524880559 @default.
• W2023282441 cites W1657501998 @default.
• W2023282441 cites W196233321 @default.
• W2023282441 cites W1968537482 @default.
• W2023282441 cites W1981186155 @default.
• W2023282441 cites W1990208536 @default.
• W2023282441 cites W2004989952 @default.
• W2023282441 cites W2006868005 @default.
• W2023282441 cites W2010512371 @default.
• W2023282441 cites W2012810666 @default.
• W2023282441 cites W2030383107 @default.
• W2023282441 cites W2033456272 @default.
• W2023282441 cites W2037968874 @default.
• W2023282441 cites W2043779377 @default.
• W2023282441 cites W2044161215 @default.
• W2023282441 cites W2044396715 @default.
• W2023282441 cites W2046273928 @default.
• W2023282441 cites W2050618345 @default.
• W2023282441 cites W2058911589 @default.
• W2023282441 cites W2060524572 @default.
• W2023282441 cites W2077298431 @default.
• W2023282441 cites W2077382981 @default.
• W2023282441 cites W2081661572 @default.
• W2023282441 cites W2082444273 @default.
• W2023282441 cites W2092762207 @default.
• W2023282441 cites W2094741111 @default.
• W2023282441 cites W2109549659 @default.
• W2023282441 cites W2113616556 @default.
• W2023282441 cites W2126740905 @default.
• W2023282441 cites W2142678626 @default.
• W2023282441 cites W2151582646 @default.
• W2023282441 cites W2152747296 @default.
• W2023282441 cites W2314517383 @default.
• W2023282441 cites W249283994 @default.
• W2023282441 doi "https://doi.org/10.1371/journal.pone.0116004" @default.
• W2023282441 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4338057" @default.
• W2023282441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25706953" @default.
• W2023282441 hasPublicationYear "2015" @default.
• W2023282441 type Work @default.
• W2023282441 sameAs 2023282441 @default.
• W2023282441 citedByCount "25" @default.
• W2023282441 countsByYear W20232824412015 @default.
• W2023282441 countsByYear W20232824412016 @default.
• W2023282441 countsByYear W20232824412017 @default.
• W2023282441 countsByYear W20232824412018 @default.
• W2023282441 countsByYear W20232824412019 @default.
• W2023282441 countsByYear W20232824412020 @default.
• W2023282441 countsByYear W20232824412021 @default.
• W2023282441 countsByYear W20232824412022 @default.
• W2023282441 crossrefType "journal-article" @default.
• W2023282441 hasAuthorship W2023282441A5001182395 @default.
• W2023282441 hasAuthorship W2023282441A5010450792 @default.
• W2023282441 hasAuthorship W2023282441A5012028701 @default.
• W2023282441 hasAuthorship W2023282441A5047700658 @default.
• W2023282441 hasAuthorship W2023282441A5059792777 @default.
• W2023282441 hasAuthorship W2023282441A5082653476 @default.
• W2023282441 hasAuthorship W2023282441A5091545614 @default.
• W2023282441 hasBestOaLocation W20232824411 @default.
• W2023282441 hasConcept C104317684 @default.
• W2023282441 hasConcept C138885662 @default.
• W2023282441 hasConcept C150194340 @default.
• W2023282441 hasConcept C153911025 @default.
• W2023282441 hasConcept C179926584 @default.
• W2023282441 hasConcept C18903297 @default.
• W2023282441 hasConcept C196843134 @default.
• W2023282441 hasConcept C20719415 @default.
• W2023282441 hasConcept C2779965526 @default.
• W2023282441 hasConcept C41895202 @default.
• W2023282441 hasConcept C53345823 @default.
• W2023282441 hasConcept C54355233 @default.
• W2023282441 hasConcept C86339819 @default.
• W2023282441 hasConcept C86803240 @default.
• W2023282441 hasConcept C87073359 @default.
• W2023282441 hasConcept C95444343 @default.
• W2023282441 hasConceptScore W2023282441C104317684 @default.
• W2023282441 hasConceptScore W2023282441C138885662 @default.
• W2023282441 hasConceptScore W2023282441C150194340 @default.
• W2023282441 hasConceptScore W2023282441C153911025 @default.
• W2023282441 hasConceptScore W2023282441C179926584 @default.
• W2023282441 hasConceptScore W2023282441C18903297 @default.
• W2023282441 hasConceptScore W2023282441C196843134 @default.
• W2023282441 hasConceptScore W2023282441C20719415 @default.
• W2023282441 hasConceptScore W2023282441C2779965526 @default.
• W2023282441 hasConceptScore W2023282441C41895202 @default.
• W2023282441 hasConceptScore W2023282441C53345823 @default.

• next