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- W2023283546 abstract "The hemorrhagic factors from the venoms of Naja naja, Agkistrodon piscivorus and Apis mellifera have been fractionated on Sephadex G 50. Different polypeptides with a molecular weight of less than 10·000 are responsible for the hemorrhagic activity. The hemorrhagic effect observed on canine lung surface caused by bee venom cannot be attributed to phospholipase A activity. Although the snake venom fractions which induced hemorrhages possessed phospholipase A activity, it appears that the enzyme is not responsible for the hemorrhages. Heparin was found to form an inactive complex with the hemorrhagic factors of Naja naja and bee venom, whereas the hemorrhagic activity of Agkistrodon piscivorus venom was unaffected by heparin. Protamine could release the hemorrhagic factor in an active form, from the inactive complexes. Esterase activity of Agkistrodon piscivorus venom and Bothrops jararaca can be inhibited by Trasylol (R)." @default.
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- W2023283546 date "1970-08-01" @default.
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- W2023283546 title "Comparison of hemorrhagic factors of the venoms of Naja naja, Agkistrodon piscivorus and Apis mellifera" @default.
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- W2023283546 doi "https://doi.org/10.1016/0006-2952(70)90264-9" @default.
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