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- W2023285261 abstract "The adverse effects of certain antihypertensive medications, most notably diuretics and β blockers, on serum lipids, glucose, and potassium may explain why control of hypertension has not been accompanied by declines in coronary artery disease. Evidence indicates that angiotensin-converting enzyme (ACE) inhibitors, including quinapril, the newest member of this class of drugs, have no deleterious effects on these coronary risk factors. In addition to differences in chemical structure, the unique activity of quinapril at the local tissue level might to some degree explain its comparatively favorable clinical profile. Consequently, ACE inhibiting agents may be better choices for the management of patients with mild-to-moderately elevated blood pressure. However, controlled clinical trials with these drugs are needed to determine their impact on events related to coronary artery disease." @default.
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- W2023285261 date "1992-04-01" @default.
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- W2023285261 title "Effects of antihypertensive agents on coronary artery disease risk factors" @default.
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- W2023285261 doi "https://doi.org/10.1016/0002-9149(92)90279-8" @default.
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