FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023288212> ?p ?o ?g. }

• W2023288212 endingPage "318" @default.
• W2023288212 startingPage "311" @default.
• W2023288212 abstract "Summary The objective here was to evaluate the acute effects of induced arthritis on synovial fluid (SF) levels of matrix metalloproteinases (MMP) ‐2, ‐8 and ‐9 in horses. To evaluate MMP‐2 and ‐9 activities and the effect of non‐steroidal anti‐inflammatory drug (NSAID) bufexamac during remission from acute arthritis. Aseptic arthritis was induced in 24 Standardbred horses using 20 mg of amphotericin B as a single intra‐articular (IA) injection in the right intercarpal joint. After 1 week and 2 weeks, horses were treated intra‐articularly with 10, 20, or 40 mg of bufexamac suspension or with sterile saline solution as control. SF was sampled prior to induction and at weekly intervals for 5 weeks. Fluids were evaluated for MMP‐2 and MMP‐9 activity by gelatin zymography or for MMP‐8 immunoreactivity by Western Blotting. IA injection of amphotericin B consistently resulted in significant increase in the immunoreactivity of MMP‐8 and activity of both the latent and the active forms of MMP‐2 and ‐9, among which the active form of MMP‐2 increased the most. MMP‐9 levels declined to pre‐induction levels within 2 weeks, whereas levels of MMP‐2 remained still high after 5 weeks. Treatment with bufexamac did not significantly affect levels of gelatinolytic MMP. Results suggest that after acute arthritis of horses, elevated MMP activity is present in the joint, for several weeks, to a degree that could promote cartilage degradation, and treatment with the NSAID bufexamac is not likely to affect that. Furthermore, analysing levels of MMP‐9 activity and especially levels of active forms of MMP‐2 activity may be valuable to predict the time of occurrence of arthritis in horses." @default.
• W2023288212 created "2016-06-24" @default.
• W2023288212 creator A5001824876 @default.
• W2023288212 creator A5025399664 @default.
• W2023288212 creator A5064266175 @default.
• W2023288212 creator A5089356920 @default.
• W2023288212 date "2006-07-20" @default.
• W2023288212 modified "2023-10-10" @default.
• W2023288212 title "Changes in MMP-2 and -9 Activity and MMP-8 Reactivity After Amphotericin B Induced Synovitis and Treatment with Bufexamac" @default.
• W2023288212 cites W1586814698 @default.
• W2023288212 cites W1695507732 @default.
• W2023288212 cites W1894541755 @default.
• W2023288212 cites W1896827225 @default.
• W2023288212 cites W1966260445 @default.
• W2023288212 cites W1966456286 @default.
• W2023288212 cites W1968479070 @default.
• W2023288212 cites W1969409619 @default.
• W2023288212 cites W1972422985 @default.
• W2023288212 cites W1973184428 @default.
• W2023288212 cites W1978554216 @default.
• W2023288212 cites W1982828943 @default.
• W2023288212 cites W1986692879 @default.
• W2023288212 cites W2002937803 @default.
• W2023288212 cites W2009021998 @default.
• W2023288212 cites W2014636270 @default.
• W2023288212 cites W2022749981 @default.
• W2023288212 cites W2023560282 @default.
• W2023288212 cites W2024393672 @default.
• W2023288212 cites W2035370445 @default.
• W2023288212 cites W2051347744 @default.
• W2023288212 cites W2060410577 @default.
• W2023288212 cites W2063412654 @default.
• W2023288212 cites W2066974794 @default.
• W2023288212 cites W2072126842 @default.
• W2023288212 cites W2075333014 @default.
• W2023288212 cites W2085227055 @default.
• W2023288212 cites W2086592513 @default.
• W2023288212 cites W2087628254 @default.
• W2023288212 cites W2088804413 @default.
• W2023288212 cites W2095054225 @default.
• W2023288212 cites W2095512005 @default.
• W2023288212 cites W2099596009 @default.
• W2023288212 cites W2103023964 @default.
• W2023288212 cites W2136703917 @default.
• W2023288212 cites W2145377797 @default.
• W2023288212 cites W2153055943 @default.
• W2023288212 cites W2154401382 @default.
• W2023288212 cites W2167676746 @default.
• W2023288212 cites W2327403075 @default.
• W2023288212 cites W2394535219 @default.
• W2023288212 cites W2406417488 @default.
• W2023288212 doi "https://doi.org/10.1111/j.1439-0442.2006.00837.x" @default.
• W2023288212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16901276" @default.
• W2023288212 hasPublicationYear "2006" @default.
• W2023288212 type Work @default.
• W2023288212 sameAs 2023288212 @default.
• W2023288212 citedByCount "13" @default.
• W2023288212 countsByYear W20232882122013 @default.
• W2023288212 countsByYear W20232882122015 @default.
• W2023288212 countsByYear W20232882122016 @default.
• W2023288212 countsByYear W20232882122017 @default.
• W2023288212 countsByYear W20232882122018 @default.
• W2023288212 countsByYear W20232882122020 @default.
• W2023288212 countsByYear W20232882122021 @default.
• W2023288212 crossrefType "journal-article" @default.
• W2023288212 hasAuthorship W2023288212A5001824876 @default.
• W2023288212 hasAuthorship W2023288212A5025399664 @default.
• W2023288212 hasAuthorship W2023288212A5064266175 @default.
• W2023288212 hasAuthorship W2023288212A5089356920 @default.
• W2023288212 hasConcept C109523444 @default.
• W2023288212 hasConcept C126322002 @default.
• W2023288212 hasConcept C141071460 @default.
• W2023288212 hasConcept C142724271 @default.
• W2023288212 hasConcept C204787440 @default.
• W2023288212 hasConcept C2776164576 @default.
• W2023288212 hasConcept C2776268809 @default.
• W2023288212 hasConcept C2777077863 @default.
• W2023288212 hasConcept C2777397205 @default.
• W2023288212 hasConcept C2779244835 @default.
• W2023288212 hasConcept C2779771469 @default.
• W2023288212 hasConcept C2781059491 @default.
• W2023288212 hasConcept C71924100 @default.
• W2023288212 hasConceptScore W2023288212C109523444 @default.
• W2023288212 hasConceptScore W2023288212C126322002 @default.
• W2023288212 hasConceptScore W2023288212C141071460 @default.
• W2023288212 hasConceptScore W2023288212C142724271 @default.
• W2023288212 hasConceptScore W2023288212C204787440 @default.
• W2023288212 hasConceptScore W2023288212C2776164576 @default.
• W2023288212 hasConceptScore W2023288212C2776268809 @default.
• W2023288212 hasConceptScore W2023288212C2777077863 @default.
• W2023288212 hasConceptScore W2023288212C2777397205 @default.
• W2023288212 hasConceptScore W2023288212C2779244835 @default.
• W2023288212 hasConceptScore W2023288212C2779771469 @default.
• W2023288212 hasConceptScore W2023288212C2781059491 @default.
• W2023288212 hasConceptScore W2023288212C71924100 @default.
• W2023288212 hasIssue "6" @default.
• W2023288212 hasLocation W20232882121 @default.
• W2023288212 hasLocation W20232882122 @default.

• next