FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023304613> ?p ?o ?g. }

• W2023304613 abstract "1 alpha,25-Dihydroxyvitamin D3-26,23-lactone [1 alpha,25(OH)2D3-26,23-lactone] was compared to 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3] in terms of their stimulation, in vivo, of intestinal calcium transport and mobilization of calcium from bone in the rat (the two classic vitamin D-mediated responses), and their relative binding to the chick intestinal receptor for 1 alpha,25(OH)2D3, 1 alpha,25-(OH)2D3-26,23-lactone was found to be only one-thirtieth as active as 1 alpha,25-(OH)2D3 in the stimulation of intestinal calcium transport and was found to mediate a significant reduction in the steady-state serum calcium levels. Associated with the reduction in serum calcium was a significant increase in urinary calcium excretion for 24 h after the administration of the steroid. Prior administration of 1 alpha,25(OH)2D3-26,23-lactone partially blocked the actions of a subsequently administered dose of 1 alpha,25(OH)2D3 in increasing serum calcium levels, but did not affect the action of 1 alpha,25(OH)2D3 in stimulating intestinal calcium transport. The binding affinity of 1 alpha,25(OH)2D3-26,23-lactone to the chick intestinal cytosol receptor protein was observed to be 670 times lower than that of 1,25-(OH)2D3 which indicates that perturbation of the 25-hydroxylated side chain by formation of the 26,23-lactone causes a significant reduction in ligand affinity for the receptor." @default.
• W2023304613 created "2016-06-24" @default.
• W2023304613 creator A5034584507 @default.
• W2023304613 creator A5056143820 @default.
• W2023304613 creator A5069194378 @default.
• W2023304613 date "1984-02-01" @default.
• W2023304613 modified "2023-09-24" @default.
• W2023304613 title "Biological activity assessment of 1α,25-dihydroxyvitamin D3-26,23-lactone in the rat" @default.
• W2023304613 cites W1518872448 @default.
• W2023304613 cites W1535146651 @default.
• W2023304613 cites W157715041 @default.
• W2023304613 cites W1880811998 @default.
• W2023304613 cites W1964548913 @default.
• W2023304613 cites W1969669209 @default.
• W2023304613 cites W1990406877 @default.
• W2023304613 cites W1999327997 @default.
• W2023304613 cites W2002655917 @default.
• W2023304613 cites W2005069111 @default.
• W2023304613 cites W2016592962 @default.
• W2023304613 cites W2023662338 @default.
• W2023304613 cites W2028184897 @default.
• W2023304613 cites W2048924343 @default.
• W2023304613 cites W2065776788 @default.
• W2023304613 cites W2078234510 @default.
• W2023304613 cites W2130557891 @default.
• W2023304613 cites W2280737718 @default.
• W2023304613 cites W2400212997 @default.
• W2023304613 cites W2409128807 @default.
• W2023304613 cites W54881700 @default.
• W2023304613 doi "https://doi.org/10.1016/0022-4731(84)90131-6" @default.
• W2023304613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6323873" @default.
• W2023304613 hasPublicationYear "1984" @default.
• W2023304613 type Work @default.
• W2023304613 sameAs 2023304613 @default.
• W2023304613 citedByCount "25" @default.
• W2023304613 countsByYear W20233046132012 @default.
• W2023304613 countsByYear W20233046132016 @default.
• W2023304613 countsByYear W20233046132018 @default.
• W2023304613 countsByYear W20233046132019 @default.
• W2023304613 crossrefType "journal-article" @default.
• W2023304613 hasAuthorship W2023304613A5034584507 @default.
• W2023304613 hasAuthorship W2023304613A5056143820 @default.
• W2023304613 hasAuthorship W2023304613A5069194378 @default.
• W2023304613 hasConcept C116073593 @default.
• W2023304613 hasConcept C124490489 @default.
• W2023304613 hasConcept C126322002 @default.
• W2023304613 hasConcept C134018914 @default.
• W2023304613 hasConcept C150903083 @default.
• W2023304613 hasConcept C159110408 @default.
• W2023304613 hasConcept C170493617 @default.
• W2023304613 hasConcept C178790620 @default.
• W2023304613 hasConcept C185592680 @default.
• W2023304613 hasConcept C202751555 @default.
• W2023304613 hasConcept C207001950 @default.
• W2023304613 hasConcept C24998067 @default.
• W2023304613 hasConcept C2775944032 @default.
• W2023304613 hasConcept C2776079296 @default.
• W2023304613 hasConcept C2776612806 @default.
• W2023304613 hasConcept C2776940978 @default.
• W2023304613 hasConcept C49453240 @default.
• W2023304613 hasConcept C519063684 @default.
• W2023304613 hasConcept C55493867 @default.
• W2023304613 hasConcept C64943373 @default.
• W2023304613 hasConcept C71924100 @default.
• W2023304613 hasConcept C86803240 @default.
• W2023304613 hasConcept C87975464 @default.
• W2023304613 hasConceptScore W2023304613C116073593 @default.
• W2023304613 hasConceptScore W2023304613C124490489 @default.
• W2023304613 hasConceptScore W2023304613C126322002 @default.
• W2023304613 hasConceptScore W2023304613C134018914 @default.
• W2023304613 hasConceptScore W2023304613C150903083 @default.
• W2023304613 hasConceptScore W2023304613C159110408 @default.
• W2023304613 hasConceptScore W2023304613C170493617 @default.
• W2023304613 hasConceptScore W2023304613C178790620 @default.
• W2023304613 hasConceptScore W2023304613C185592680 @default.
• W2023304613 hasConceptScore W2023304613C202751555 @default.
• W2023304613 hasConceptScore W2023304613C207001950 @default.
• W2023304613 hasConceptScore W2023304613C24998067 @default.
• W2023304613 hasConceptScore W2023304613C2775944032 @default.
• W2023304613 hasConceptScore W2023304613C2776079296 @default.
• W2023304613 hasConceptScore W2023304613C2776612806 @default.
• W2023304613 hasConceptScore W2023304613C2776940978 @default.
• W2023304613 hasConceptScore W2023304613C49453240 @default.
• W2023304613 hasConceptScore W2023304613C519063684 @default.
• W2023304613 hasConceptScore W2023304613C55493867 @default.
• W2023304613 hasConceptScore W2023304613C64943373 @default.
• W2023304613 hasConceptScore W2023304613C71924100 @default.
• W2023304613 hasConceptScore W2023304613C86803240 @default.
• W2023304613 hasConceptScore W2023304613C87975464 @default.
• W2023304613 hasLocation W20233046131 @default.
• W2023304613 hasLocation W20233046132 @default.
• W2023304613 hasOpenAccess W2023304613 @default.
• W2023304613 hasPrimaryLocation W20233046131 @default.
• W2023304613 hasRelatedWork W1999545086 @default.
• W2023304613 hasRelatedWork W2024089434 @default.
• W2023304613 hasRelatedWork W2042131050 @default.
• W2023304613 hasRelatedWork W2068831921 @default.
• W2023304613 hasRelatedWork W2091829139 @default.
• W2023304613 hasRelatedWork W2106814035 @default.
• W2023304613 hasRelatedWork W2158651421 @default.

• next