Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023307888> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2023307888 endingPage "619" @default.
- W2023307888 startingPage "614" @default.
- W2023307888 abstract "Gloverin is an inducible antibacterial insect protein isolated from pupae of the giant silk moth Hyalophora. It is a basic (pI 8.5) protein with a molecular mass of 13.8 kDa, containing a large number of glycine residues (18.5%) but no cysteine, and has an amino acid sequence that reveals no strong degree of identity with any known proteins. Gloverin inhibits the growth of Escherichia coli at a minimal concentration of 1-3 microM, i.e. less than 5% of the concentration of gloverin in the hemolymph of infected pupae. The prime effect of gloverin, following its interaction with lipopolysaccharide (LPS) in the bacterial envelope, is a specific inhibition of the synthesis of vital outer membrane proteins, leading to an increased permeability of the outer membrane. The activity of gloverin is not affected by heating (100 degrees C, 10 min) but is inhibited by Mg2+ and by free LPS. The gloverin molecule will undergo conformational transitions from a monomeric random coil to an alpha-helix upon transfer from an aqueous to a hydrophobic environment, a property likely to be of importance for its interaction with cell-bound LPS. The activity of gloverin is in many respects similar to that of attacin, another antibacterial protein, originally found in Hyalophora [for a review see Boman, H. G., Faye, I., Gudmundsson, G. H., Lee, J.-Y. & Lindholm, D. A. (1991) Eur J. Biochem. 201, 23-31]." @default.
- W2023307888 created "2016-06-24" @default.
- W2023307888 creator A5017729121 @default.
- W2023307888 creator A5045001489 @default.
- W2023307888 creator A5055879385 @default.
- W2023307888 creator A5061017711 @default.
- W2023307888 date "1997-07-15" @default.
- W2023307888 modified "2023-09-27" @default.
- W2023307888 title "Gloverin, an Antibacterial Protein from the Immune Hemolymph of Hyalophora Pupae" @default.
- W2023307888 cites W131059411 @default.
- W2023307888 cites W1508619302 @default.
- W2023307888 cites W1574787285 @default.
- W2023307888 cites W1909977811 @default.
- W2023307888 cites W1944553966 @default.
- W2023307888 cites W1970621669 @default.
- W2023307888 cites W1988048149 @default.
- W2023307888 cites W1988084609 @default.
- W2023307888 cites W2009168924 @default.
- W2023307888 cites W2018309785 @default.
- W2023307888 cites W2024220427 @default.
- W2023307888 cites W2039764190 @default.
- W2023307888 cites W2052112210 @default.
- W2023307888 cites W2071140940 @default.
- W2023307888 cites W2077883609 @default.
- W2023307888 cites W2085474307 @default.
- W2023307888 cites W2100837269 @default.
- W2023307888 cites W2140472579 @default.
- W2023307888 cites W2148019102 @default.
- W2023307888 cites W310815860 @default.
- W2023307888 doi "https://doi.org/10.1111/j.1432-1033.1997.00614.x" @default.
- W2023307888 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9266704" @default.
- W2023307888 hasPublicationYear "1997" @default.
- W2023307888 type Work @default.
- W2023307888 sameAs 2023307888 @default.
- W2023307888 citedByCount "106" @default.
- W2023307888 countsByYear W20233078882012 @default.
- W2023307888 countsByYear W20233078882013 @default.
- W2023307888 countsByYear W20233078882014 @default.
- W2023307888 countsByYear W20233078882015 @default.
- W2023307888 countsByYear W20233078882016 @default.
- W2023307888 countsByYear W20233078882017 @default.
- W2023307888 countsByYear W20233078882018 @default.
- W2023307888 countsByYear W20233078882019 @default.
- W2023307888 countsByYear W20233078882020 @default.
- W2023307888 countsByYear W20233078882021 @default.
- W2023307888 countsByYear W20233078882022 @default.
- W2023307888 countsByYear W20233078882023 @default.
- W2023307888 crossrefType "journal-article" @default.
- W2023307888 hasAuthorship W2023307888A5017729121 @default.
- W2023307888 hasAuthorship W2023307888A5045001489 @default.
- W2023307888 hasAuthorship W2023307888A5055879385 @default.
- W2023307888 hasAuthorship W2023307888A5061017711 @default.
- W2023307888 hasConcept C100068826 @default.
- W2023307888 hasConcept C104317684 @default.
- W2023307888 hasConcept C146587185 @default.
- W2023307888 hasConcept C153911025 @default.
- W2023307888 hasConcept C185592680 @default.
- W2023307888 hasConcept C203014093 @default.
- W2023307888 hasConcept C2777317804 @default.
- W2023307888 hasConcept C2778754761 @default.
- W2023307888 hasConcept C46371251 @default.
- W2023307888 hasConcept C547475151 @default.
- W2023307888 hasConcept C55493867 @default.
- W2023307888 hasConcept C86803240 @default.
- W2023307888 hasConceptScore W2023307888C100068826 @default.
- W2023307888 hasConceptScore W2023307888C104317684 @default.
- W2023307888 hasConceptScore W2023307888C146587185 @default.
- W2023307888 hasConceptScore W2023307888C153911025 @default.
- W2023307888 hasConceptScore W2023307888C185592680 @default.
- W2023307888 hasConceptScore W2023307888C203014093 @default.
- W2023307888 hasConceptScore W2023307888C2777317804 @default.
- W2023307888 hasConceptScore W2023307888C2778754761 @default.
- W2023307888 hasConceptScore W2023307888C46371251 @default.
- W2023307888 hasConceptScore W2023307888C547475151 @default.
- W2023307888 hasConceptScore W2023307888C55493867 @default.
- W2023307888 hasConceptScore W2023307888C86803240 @default.
- W2023307888 hasIssue "2" @default.
- W2023307888 hasLocation W20233078881 @default.
- W2023307888 hasLocation W20233078882 @default.
- W2023307888 hasOpenAccess W2023307888 @default.
- W2023307888 hasPrimaryLocation W20233078881 @default.
- W2023307888 hasRelatedWork W1521888210 @default.
- W2023307888 hasRelatedWork W1899288461 @default.
- W2023307888 hasRelatedWork W1996358024 @default.
- W2023307888 hasRelatedWork W2026012618 @default.
- W2023307888 hasRelatedWork W2113755148 @default.
- W2023307888 hasRelatedWork W2127176165 @default.
- W2023307888 hasRelatedWork W2410372753 @default.
- W2023307888 hasRelatedWork W4243893378 @default.
- W2023307888 hasRelatedWork W4251205702 @default.
- W2023307888 hasRelatedWork W2108026771 @default.
- W2023307888 hasVolume "247" @default.
- W2023307888 isParatext "false" @default.
- W2023307888 isRetracted "false" @default.
- W2023307888 magId "2023307888" @default.
- W2023307888 workType "article" @default.