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- W2023321382 abstract "Electrospinning of polylactide–polyglycolide (PLGA)/collagen in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) to fabricate a biomimetic nanofibrous extracellular membranes for wound dressing and tissue engineering was investigated. The morphology of as-spun PLGA/collagen nanofibers was examined by scanning electron microscopy. The average diameter of electrospun nanofibers was 250 nm (range of 150–650 nm). Degradation rate of PLGA/collagen nanofibrous membranes, cytocompatibility and cellular responses to membranes, cell and nanofibers interactions, and open wound healing in rats were studied. It was found that nanofibrous membranes made of PLGA/collagen were functionally active in responses in human fibroblasts, and were very effective as wound-healing accelerators in early-stage wound healing. The empirical results in this study indicate that electrospun PLGA/collagen nanofibers may be a good candidate as a wound dressing for skin regeneration." @default.
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- W2023321382 date "2010-06-15" @default.
- W2023321382 modified "2023-10-07" @default.
- W2023321382 title "Electrospun PLGA/collagen nanofibrous membrane as early-stage wound dressing" @default.
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- W2023321382 doi "https://doi.org/10.1016/j.memsci.2010.03.012" @default.
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