FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023321624> ?p ?o ?g. }

• W2023321624 endingPage "68" @default.
• W2023321624 startingPage "63" @default.
• W2023321624 abstract "The exonuclease-based real-time polymerase chain reaction (PCR) exploits 5'-->3' exonuclease activity of Taq polymerase and measures PCR product accumulation as the reaction proceeds through a dual-labeled fluorogenic probe. The utility of this exonuclease-based PCR assay as a rapid alternative to conventional PCR for follicular lymphoma-associated t(14;18)(q32;q21) was evaluated in this study. The specificity of the assay for t(14;18) involving bcl-2 and immunoglobulin heavy-chain joining region (JH) genes was assessed by analyzing DNA from 53 patients (38 B-cell non-Hodgkin's lymphomas and 15 nonneoplastic proliferations) and correlating the exonuclease PCR data with conventional PCR results. bcl-2/JH fusion sequences were detected by exonuclease-based PCR in 24 of 25 cases shown to be bcl-2 rearranged by conventional PCR. Fusion sequences were not detected in patients who were negative by conventional PCR. The overall concordance between the two assays was 98% (52 of 53 cases concordant positive or negative). In a serial dilution study using t(14;18)-positive cell line DNA, exonuclease-based PCR detected fusion sequences at DNA concentrations of 5 pg, equivalent to 0.6 to 0.8 genomes per reaction. Thus, this study demonstrated that exonuclease-based PCR for t(14;18) is both specific and highly sensitive. The elimination of the post-PCR amplicon detection steps and the ability to quantitate the input target DNA sequences make this assay ideal for routine diagnostics and monitoring minimal residual disease." @default.
• W2023321624 created "2016-06-24" @default.
• W2023321624 creator A5022587253 @default.
• W2023321624 creator A5050082511 @default.
• W2023321624 creator A5060386553 @default.
• W2023321624 creator A5073079562 @default.
• W2023321624 date "1998-07-01" @default.
• W2023321624 modified "2023-09-27" @default.
• W2023321624 title "Novel 5′ Exonuclease-Based Real-Time PCR Assay for the Detection of t(14;18)(q32;q21) in Patients with Follicular Lymphoma" @default.
• W2023321624 cites W112480256 @default.
• W2023321624 cites W1542617164 @default.
• W2023321624 cites W1693638501 @default.
• W2023321624 cites W1968087380 @default.
• W2023321624 cites W1994091239 @default.
• W2023321624 cites W2001526641 @default.
• W2023321624 cites W2011802271 @default.
• W2023321624 cites W2022227920 @default.
• W2023321624 cites W2025635508 @default.
• W2023321624 cites W2070721758 @default.
• W2023321624 cites W2090310052 @default.
• W2023321624 cites W2129818178 @default.
• W2023321624 cites W2145684092 @default.
• W2023321624 cites W2164578725 @default.
• W2023321624 cites W2255698332 @default.
• W2023321624 cites W2315396643 @default.
• W2023321624 cites W2340105 @default.
• W2023321624 cites W25693568 @default.
• W2023321624 doi "https://doi.org/10.1016/s0002-9440(10)65546-0" @default.
• W2023321624 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1852934" @default.
• W2023321624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9665466" @default.
• W2023321624 hasPublicationYear "1998" @default.
• W2023321624 type Work @default.
• W2023321624 sameAs 2023321624 @default.
• W2023321624 citedByCount "119" @default.
• W2023321624 countsByYear W20233216242013 @default.
• W2023321624 countsByYear W20233216242015 @default.
• W2023321624 countsByYear W20233216242020 @default.
• W2023321624 crossrefType "journal-article" @default.
• W2023321624 hasAuthorship W2023321624A5022587253 @default.
• W2023321624 hasAuthorship W2023321624A5050082511 @default.
• W2023321624 hasAuthorship W2023321624A5060386553 @default.
• W2023321624 hasAuthorship W2023321624A5073079562 @default.
• W2023321624 hasBestOaLocation W20233216242 @default.
• W2023321624 hasConcept C104317684 @default.
• W2023321624 hasConcept C153911025 @default.
• W2023321624 hasConcept C159047783 @default.
• W2023321624 hasConcept C203014093 @default.
• W2023321624 hasConcept C2756471 @default.
• W2023321624 hasConcept C2777058707 @default.
• W2023321624 hasConcept C2777501222 @default.
• W2023321624 hasConcept C2778461978 @default.
• W2023321624 hasConcept C2779186596 @default.
• W2023321624 hasConcept C2779338263 @default.
• W2023321624 hasConcept C2779823535 @default.
• W2023321624 hasConcept C2781243718 @default.
• W2023321624 hasConcept C2781440490 @default.
• W2023321624 hasConcept C48023723 @default.
• W2023321624 hasConcept C49105822 @default.
• W2023321624 hasConcept C54355233 @default.
• W2023321624 hasConcept C54415193 @default.
• W2023321624 hasConcept C547475151 @default.
• W2023321624 hasConcept C552990157 @default.
• W2023321624 hasConcept C8185291 @default.
• W2023321624 hasConcept C86803240 @default.
• W2023321624 hasConceptScore W2023321624C104317684 @default.
• W2023321624 hasConceptScore W2023321624C153911025 @default.
• W2023321624 hasConceptScore W2023321624C159047783 @default.
• W2023321624 hasConceptScore W2023321624C203014093 @default.
• W2023321624 hasConceptScore W2023321624C2756471 @default.
• W2023321624 hasConceptScore W2023321624C2777058707 @default.
• W2023321624 hasConceptScore W2023321624C2777501222 @default.
• W2023321624 hasConceptScore W2023321624C2778461978 @default.
• W2023321624 hasConceptScore W2023321624C2779186596 @default.
• W2023321624 hasConceptScore W2023321624C2779338263 @default.
• W2023321624 hasConceptScore W2023321624C2779823535 @default.
• W2023321624 hasConceptScore W2023321624C2781243718 @default.
• W2023321624 hasConceptScore W2023321624C2781440490 @default.
• W2023321624 hasConceptScore W2023321624C48023723 @default.
• W2023321624 hasConceptScore W2023321624C49105822 @default.
• W2023321624 hasConceptScore W2023321624C54355233 @default.
• W2023321624 hasConceptScore W2023321624C54415193 @default.
• W2023321624 hasConceptScore W2023321624C547475151 @default.
• W2023321624 hasConceptScore W2023321624C552990157 @default.
• W2023321624 hasConceptScore W2023321624C8185291 @default.
• W2023321624 hasConceptScore W2023321624C86803240 @default.
• W2023321624 hasIssue "1" @default.
• W2023321624 hasLocation W20233216241 @default.
• W2023321624 hasLocation W20233216242 @default.
• W2023321624 hasLocation W20233216243 @default.
• W2023321624 hasLocation W20233216244 @default.
• W2023321624 hasOpenAccess W2023321624 @default.
• W2023321624 hasPrimaryLocation W20233216241 @default.
• W2023321624 hasRelatedWork W1978828438 @default.
• W2023321624 hasRelatedWork W2017901018 @default.
• W2023321624 hasRelatedWork W2018267950 @default.
• W2023321624 hasRelatedWork W2023321624 @default.
• W2023321624 hasRelatedWork W2049494208 @default.
• W2023321624 hasRelatedWork W2070721758 @default.

• next