FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023321767> ?p ?o ?g. }

• W2023321767 endingPage "27" @default.
• W2023321767 startingPage "19" @default.
• W2023321767 abstract "Idiopathic pulmonary fibrosis (IPF) is the most common disease in the subgroup of idiopathic interstitial pneumonias. It is inevitably associated to a bad prognosis, although assuming a highly variable clinical course.Patients with IPF, observed at Interstitial Lung Diseases outpatient clinic of Centro Hospitalar de São João - Porto, Portugal, were identified and clinical, functional, radiological and bronchoalveolar lavage (BAL) parameters were reviewed. Their clinical course and survival were analyzed in order to identify prognostic factors.Eighty-one patients were included, with a mean age at diagnosis of 63.8 years old. At diagnosis, the main functional abnormalities were restrictive physiology, reduced lung diffusion and exercise capacity impairment. Clinical course was mainly slowly progressive (72.3%). Ten patients (13.2%) had a rapid progression and 11 (14.5%) patients had an acute exacerbation during the course of the disease. IPF's rapid progression was associated to a higher functional impairment at diagnosis, namely in what is related with Forced Vital Capacity (FVC) and Total Lung Capacity (TLC). Median survival was 36 months. A significant difference in survival was observed among different types of clinical course - 41 months for slow progressors and 9 months for rapid progressors. Lower levels of FVC, TLC, 6th minute walk test distance and rest PaO2, and higher BAL neutrophil count were associated with poorer survival in univariate analysis.The analysis of this group of IPF patients confirms two clearly different phenotypes, slow and rapid progressors. Those phenotypes seem to have different presentations and a remarkably different natural history. These results could mean different physiopathologic pathways, which could implicate different therapeutic approaches." @default.
• W2023321767 created "2016-06-24" @default.
• W2023321767 creator A5007365878 @default.
• W2023321767 creator A5021430946 @default.
• W2023321767 creator A5028767906 @default.
• W2023321767 creator A5038990808 @default.
• W2023321767 creator A5052663157 @default.
• W2023321767 creator A5059597694 @default.
• W2023321767 creator A5065737701 @default.
• W2023321767 creator A5066251434 @default.
• W2023321767 creator A5081333333 @default.
• W2023321767 date "2013-01-01" @default.
• W2023321767 modified "2023-10-04" @default.
• W2023321767 title "Fibrose pulmonar idiopática: apresentação clínica, evolução e fatores de prognóstico basais numa coorte portuguesa" @default.
• W2023321767 cites W1512131644 @default.
• W2023321767 cites W1548223836 @default.
• W2023321767 cites W1860863518 @default.
• W2023321767 cites W1968503055 @default.
• W2023321767 cites W1970379805 @default.
• W2023321767 cites W1991660435 @default.
• W2023321767 cites W1993078339 @default.
• W2023321767 cites W1997082999 @default.
• W2023321767 cites W2001634286 @default.
• W2023321767 cites W2005591966 @default.
• W2023321767 cites W2011870650 @default.
• W2023321767 cites W2029881026 @default.
• W2023321767 cites W2036041938 @default.
• W2023321767 cites W2037681111 @default.
• W2023321767 cites W2058483311 @default.
• W2023321767 cites W2058505955 @default.
• W2023321767 cites W2065106161 @default.
• W2023321767 cites W2074000402 @default.
• W2023321767 cites W2080677332 @default.
• W2023321767 cites W2085043154 @default.
• W2023321767 cites W2092639656 @default.
• W2023321767 cites W2095309945 @default.
• W2023321767 cites W2095979797 @default.
• W2023321767 cites W2096358180 @default.
• W2023321767 cites W2098079030 @default.
• W2023321767 cites W2100059970 @default.
• W2023321767 cites W2100580906 @default.
• W2023321767 cites W2103258766 @default.
• W2023321767 cites W2113777102 @default.
• W2023321767 cites W2117681009 @default.
• W2023321767 cites W2123137799 @default.
• W2023321767 cites W2123254998 @default.
• W2023321767 cites W2124063170 @default.
• W2023321767 cites W2125078269 @default.
• W2023321767 cites W2125322938 @default.
• W2023321767 cites W2132334298 @default.
• W2023321767 cites W2138882003 @default.
• W2023321767 cites W2140334695 @default.
• W2023321767 cites W2140923971 @default.
• W2023321767 cites W2141860518 @default.
• W2023321767 cites W2141922649 @default.
• W2023321767 cites W2142941142 @default.
• W2023321767 cites W2146965595 @default.
• W2023321767 cites W2154486847 @default.
• W2023321767 cites W2157869208 @default.
• W2023321767 cites W2159852406 @default.
• W2023321767 cites W2163595789 @default.
• W2023321767 cites W2163779649 @default.
• W2023321767 cites W2167189518 @default.
• W2023321767 cites W2167383172 @default.
• W2023321767 cites W2416914730 @default.
• W2023321767 cites W2510123827 @default.
• W2023321767 cites W3022958008 @default.
• W2023321767 cites W3028069669 @default.
• W2023321767 cites W4231860663 @default.
• W2023321767 cites W4245666729 @default.
• W2023321767 doi "https://doi.org/10.1016/j.rppneu.2012.05.002" @default.
• W2023321767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22819487" @default.
• W2023321767 hasPublicationYear "2013" @default.
• W2023321767 type Work @default.
• W2023321767 sameAs 2023321767 @default.
• W2023321767 citedByCount "12" @default.
• W2023321767 countsByYear W20233217672013 @default.
• W2023321767 countsByYear W20233217672014 @default.
• W2023321767 countsByYear W20233217672015 @default.
• W2023321767 countsByYear W20233217672016 @default.
• W2023321767 countsByYear W20233217672017 @default.
• W2023321767 countsByYear W20233217672019 @default.
• W2023321767 countsByYear W20233217672020 @default.
• W2023321767 countsByYear W20233217672021 @default.
• W2023321767 countsByYear W20233217672023 @default.
• W2023321767 crossrefType "journal-article" @default.
• W2023321767 hasAuthorship W2023321767A5007365878 @default.
• W2023321767 hasAuthorship W2023321767A5021430946 @default.
• W2023321767 hasAuthorship W2023321767A5028767906 @default.
• W2023321767 hasAuthorship W2023321767A5038990808 @default.
• W2023321767 hasAuthorship W2023321767A5052663157 @default.
• W2023321767 hasAuthorship W2023321767A5059597694 @default.
• W2023321767 hasAuthorship W2023321767A5065737701 @default.
• W2023321767 hasAuthorship W2023321767A5066251434 @default.
• W2023321767 hasAuthorship W2023321767A5081333333 @default.
• W2023321767 hasBestOaLocation W20233217671 @default.
• W2023321767 hasConcept C126322002 @default.
• W2023321767 hasConcept C144301174 @default.

• next