Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023332571> ?p ?o ?g. }
- W2023332571 endingPage "469" @default.
- W2023332571 startingPage "462" @default.
- W2023332571 abstract "Pancreatic cancer has a very poor prognosis, in part due to its diagnosis at late stages of the disease and to limited response to chemotherapy and radiotherapy. The vast majority of pancreatic cancers are classified as pancreatic ductal adenocarcinomas (PDACs). Despite advances in knowledge on the cellular origin of PDAC or the involvement of signal transduction pathways therein, many questions remain unanswered. In this review, we summarize recent findings and current hypotheses regarding these two questions. Since pancreatitis is a risk factor for human PDAC, and the latter proceeds with an intense fibrotic reaction, we also analyze the role of the stroma in PDAC progression. An improved understanding of these key aspects for PDAC ontogeny will open new avenues for tumor prevention, early detection, and improved therapy." @default.
- W2023332571 created "2016-06-24" @default.
- W2023332571 creator A5010520402 @default.
- W2023332571 creator A5039737999 @default.
- W2023332571 creator A5060086359 @default.
- W2023332571 creator A5071973404 @default.
- W2023332571 date "2008-10-01" @default.
- W2023332571 modified "2023-10-16" @default.
- W2023332571 title "Pancreatic Ductal Adenocarcinoma: Cellular Origin, Signaling Pathways and Stroma Contribution" @default.
- W2023332571 cites W1530685593 @default.
- W2023332571 cites W1568038787 @default.
- W2023332571 cites W1721336579 @default.
- W2023332571 cites W1964064067 @default.
- W2023332571 cites W1966427973 @default.
- W2023332571 cites W1973758000 @default.
- W2023332571 cites W1980741832 @default.
- W2023332571 cites W1981104423 @default.
- W2023332571 cites W1982781304 @default.
- W2023332571 cites W1984162437 @default.
- W2023332571 cites W1986879690 @default.
- W2023332571 cites W1991251040 @default.
- W2023332571 cites W1992995822 @default.
- W2023332571 cites W1993470907 @default.
- W2023332571 cites W1995027351 @default.
- W2023332571 cites W1995851961 @default.
- W2023332571 cites W2002355858 @default.
- W2023332571 cites W2011550114 @default.
- W2023332571 cites W2019264784 @default.
- W2023332571 cites W2019384565 @default.
- W2023332571 cites W2023121460 @default.
- W2023332571 cites W2025397278 @default.
- W2023332571 cites W2025970479 @default.
- W2023332571 cites W2031300004 @default.
- W2023332571 cites W2042978848 @default.
- W2023332571 cites W2044935342 @default.
- W2023332571 cites W2045042058 @default.
- W2023332571 cites W2050164769 @default.
- W2023332571 cites W2056646351 @default.
- W2023332571 cites W2056822884 @default.
- W2023332571 cites W2058693971 @default.
- W2023332571 cites W2063188304 @default.
- W2023332571 cites W2065871203 @default.
- W2023332571 cites W2066135299 @default.
- W2023332571 cites W2067495748 @default.
- W2023332571 cites W2070237246 @default.
- W2023332571 cites W2073676014 @default.
- W2023332571 cites W2073826397 @default.
- W2023332571 cites W2077325021 @default.
- W2023332571 cites W2079998750 @default.
- W2023332571 cites W2084277057 @default.
- W2023332571 cites W2093157637 @default.
- W2023332571 cites W2095605427 @default.
- W2023332571 cites W2097755642 @default.
- W2023332571 cites W2098036848 @default.
- W2023332571 cites W2100562940 @default.
- W2023332571 cites W2100801124 @default.
- W2023332571 cites W2108100098 @default.
- W2023332571 cites W2112573682 @default.
- W2023332571 cites W2119651686 @default.
- W2023332571 cites W2126663928 @default.
- W2023332571 cites W2128007109 @default.
- W2023332571 cites W2128863223 @default.
- W2023332571 cites W2131170195 @default.
- W2023332571 cites W2134226456 @default.
- W2023332571 cites W2140343175 @default.
- W2023332571 cites W2140923392 @default.
- W2023332571 cites W2142129456 @default.
- W2023332571 cites W2143291443 @default.
- W2023332571 cites W2145639699 @default.
- W2023332571 cites W2146466993 @default.
- W2023332571 cites W2148054025 @default.
- W2023332571 cites W2151638621 @default.
- W2023332571 cites W2156219329 @default.
- W2023332571 cites W2156802024 @default.
- W2023332571 doi "https://doi.org/10.1159/000151537" @default.
- W2023332571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18724072" @default.
- W2023332571 hasPublicationYear "2008" @default.
- W2023332571 type Work @default.
- W2023332571 sameAs 2023332571 @default.
- W2023332571 citedByCount "30" @default.
- W2023332571 countsByYear W20233325712012 @default.
- W2023332571 countsByYear W20233325712013 @default.
- W2023332571 countsByYear W20233325712014 @default.
- W2023332571 countsByYear W20233325712015 @default.
- W2023332571 countsByYear W20233325712016 @default.
- W2023332571 countsByYear W20233325712018 @default.
- W2023332571 countsByYear W20233325712019 @default.
- W2023332571 countsByYear W20233325712022 @default.
- W2023332571 crossrefType "journal-article" @default.
- W2023332571 hasAuthorship W2023332571A5010520402 @default.
- W2023332571 hasAuthorship W2023332571A5039737999 @default.
- W2023332571 hasAuthorship W2023332571A5060086359 @default.
- W2023332571 hasAuthorship W2023332571A5071973404 @default.
- W2023332571 hasConcept C121608353 @default.
- W2023332571 hasConcept C126322002 @default.
- W2023332571 hasConcept C142724271 @default.
- W2023332571 hasConcept C143998085 @default.
- W2023332571 hasConcept C204232928 @default.