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- W2023340925 abstract "To identify brain areas involved in ethanol-induced Pavlovian conditioning, brains of male DBA/2J mice were immunohistochemically analyzed for FOS expression after exposure to a conditioned stimulus (CS) previously paired with ethanol (2 g/kg) in two experiments. Mice were trained with a procedure that normally produces place preference (Before: ethanol before the CS) or one that normally produces place aversion (After: ethanol after the CS). Control groups received unpaired ethanol injections in the home cage (Delay) or saline only (Naïve). On the test day, mice were exposed to the 5-min CS 90 min before sacrifice. Before groups showed a conditioned increase in activity, whereas the After group showed a conditioned decrease in activity. FOS expression after a drug-free CS exposure was significantly higher in Before-group mice than in control mice in the bed nucleus of the stria terminalis (Experiment 1) and anterior ventral tegmental area (Experiments 1–2). Conditioned FOS responses were also seen in areas of the extended amygdala and hippocampus (Experiment 2). However, no conditioned FOS changes were seen in any brain area examined in After-group mice. Overall, these data suggest an important role for the mesolimbic dopamine pathway, extended amygdala and hippocampus in ethanol-induced conditioning." @default.
- W2023340925 created "2016-06-24" @default.
- W2023340925 creator A5003072259 @default.
- W2023340925 creator A5003891946 @default.
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- W2023340925 date "2007-06-01" @default.
- W2023340925 modified "2023-09-23" @default.
- W2023340925 title "FOS expression induced by an ethanol-paired conditioned stimulus" @default.
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- W2023340925 doi "https://doi.org/10.1016/j.pbb.2007.04.017" @default.
- W2023340925 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2025694" @default.
- W2023340925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17531293" @default.
- W2023340925 hasPublicationYear "2007" @default.
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