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- W2023341244 abstract "ETHAMBUTOL has found wide clinical acceptance as an effective agent for the treatment of Mycobacterium tuberculosis infections in man. Of the recognized side effects associated with the administration of ethambutol, ophthalmic toxicity has received the most attention.We have found a substantial increase in the serum urate concentration in patients being treated with ethambutol. The present study was undertaken to establish the frequency, mechanism and importance of this effect in man.Materials and MethodsThe effect of prolonged therapy with ethambutol in a daily dose of 12 to 19 mg per kilogram of body weight on the metabolism of uric . . ." @default.
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- W2023341244 date "1972-04-06" @default.
- W2023341244 modified "2023-09-24" @default.
- W2023341244 title "Hyperuricemia Due to Ethambutol" @default.
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- W2023341244 doi "https://doi.org/10.1056/nejm197204062861407" @default.
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