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• W2023342883 abstract "Purpose . The relationship between number of laser burns of cyclophotocoagulation (CPC) and intraocular pressure (IOP) reduction is unknown. This animal model was established to reveal a possible dose-response-relationship between the number of applied laser burns and the IOP lowering effect. Methods . 30 chinchilla bastard rabbits were divided into 5 groups and treated with either 1, 5, 10, 20, or 30 CPC burns, respectively. IOP was followed up for 1 week. IOP reduction of a single 30-burn treatment was compared with a fractionated treatment (three sessions; one week in between; 10 burns/session). Results . IOP reduction increases nonlinearly with the number of CPC burns (max.<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mo>-</mml:mo><mml:mn>6.1</mml:mn><mml:mo>±</mml:mo><mml:mn>1.4</mml:mn></mml:math> mmHg). Fractionated treatment shows similar IOP reduction with less complications and more constant results compared to single session treatment. Conclusions . The study reveals a complex relationship between IOP reduction and the number of CPC burns. Fractionated CPC gives comparable IOP reduction at a higher degree of safety." @default.
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• W2023342883 date "2014-01-01" @default.
• W2023342883 modified "2023-09-25" @default.
• W2023342883 title "Dose-Response-Relationship between Number of Laser Burns and IOP Reduction in Cyclophotocoagulation: An Animal Study" @default.
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• W2023342883 doi "https://doi.org/10.1155/2014/983102" @default.
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