FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023343401> ?p ?o ?g. }

• W2023343401 endingPage "83" @default.
• W2023343401 startingPage "71" @default.
• W2023343401 abstract "Botryllus schlosseri is a colonial ascidian whose asexually derived, clonally modular systems of zooids exhibit developmental synchrony. The blastogenic cycle culminates in a phase of programmed cell and zooid death called takeover, in which all functional zooids die over a 30 hr period, and are replaced by a new generation of individuals. Because of the weekly recurrence and magnitude of visceral death in this model organism, we have begun to characterize the mechanisms that govern takeover. Here we describe a monoclonal antibody (B3F12.9) that recognizes a novel 57 Kd polypeptide (under reducing conditions) localized to the perivisceral extracellular matrix (PVEM) of buds and zooids, as well as blood cells of Botryllus by immunofluorescence and immunogold labeling of tissue sections. During their active feeding phase, zooids exhibited a uniform labeling pattern of PVEM along their anteroposterior (A-P) axis. At the onset of takeover (T = 3 hr), B3F12.9 immunostaining became diffuse or absent at the anterior end, which paralleled the axis of contraction of the dying zooid, whereas the posterior end retained its labeling integrity. During mid (T = 15 hr) to late (T = 28 hr) takeover, issue damage was extensive, large blood macrophages and other B3F12.9 immunoreactive blood cells invaded the peribranchial cavity, whereas PVEM labeling gradually disappeared along the entire A-P axis. These findings indicate that takeover is a dynamic process in which extracellular matrix breakdown proceeds in a polarized fashion, beginning at the anterior end of each zooid and gradually propagating toward the posterior end. © 1992 Wiley-Liss, Inc." @default.
• W2023343401 created "2016-06-24" @default.
• W2023343401 creator A5004383514 @default.
• W2023343401 creator A5051491939 @default.
• W2023343401 creator A5082894731 @default.
• W2023343401 date "1992-05-01" @default.
• W2023343401 modified "2023-10-17" @default.
• W2023343401 title "A cyclical, developmentally-regulated death phenomenon in a colonial urochordate" @default.
• W2023343401 cites W1180108146 @default.
• W2023343401 cites W123794703 @default.
• W2023343401 cites W1589415602 @default.
• W2023343401 cites W1832595981 @default.
• W2023343401 cites W1924646174 @default.
• W2023343401 cites W1934231065 @default.
• W2023343401 cites W1956253188 @default.
• W2023343401 cites W1969331809 @default.
• W2023343401 cites W1972364920 @default.
• W2023343401 cites W1976133790 @default.
• W2023343401 cites W1976312800 @default.
• W2023343401 cites W1983645902 @default.
• W2023343401 cites W1988047904 @default.
• W2023343401 cites W2001073162 @default.
• W2023343401 cites W2001680431 @default.
• W2023343401 cites W2003054104 @default.
• W2023343401 cites W2003501749 @default.
• W2023343401 cites W2014321075 @default.
• W2023343401 cites W2024232113 @default.
• W2023343401 cites W2030273261 @default.
• W2023343401 cites W2032057086 @default.
• W2023343401 cites W2045008512 @default.
• W2023343401 cites W2045800989 @default.
• W2023343401 cites W204580905 @default.
• W2023343401 cites W2048010506 @default.
• W2023343401 cites W2049485776 @default.
• W2023343401 cites W2051535569 @default.
• W2023343401 cites W2052238319 @default.
• W2023343401 cites W2053521525 @default.
• W2023343401 cites W2058365755 @default.
• W2023343401 cites W2063765957 @default.
• W2023343401 cites W2083721668 @default.
• W2023343401 cites W2085124463 @default.
• W2023343401 cites W2091308738 @default.
• W2023343401 cites W2100193790 @default.
• W2023343401 cites W2100837269 @default.
• W2023343401 cites W2101108802 @default.
• W2023343401 cites W2146449876 @default.
• W2023343401 cites W2150912846 @default.
• W2023343401 cites W2152257877 @default.
• W2023343401 cites W2285250728 @default.
• W2023343401 cites W2411984829 @default.
• W2023343401 cites W2525633239 @default.
• W2023343401 cites W2764725850 @default.
• W2023343401 cites W4232534952 @default.
• W2023343401 doi "https://doi.org/10.1002/aja.1001940109" @default.
• W2023343401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1421521" @default.
• W2023343401 hasPublicationYear "1992" @default.
• W2023343401 type Work @default.
• W2023343401 sameAs 2023343401 @default.
• W2023343401 citedByCount "78" @default.
• W2023343401 countsByYear W20233434012012 @default.
• W2023343401 countsByYear W20233434012013 @default.
• W2023343401 countsByYear W20233434012014 @default.
• W2023343401 countsByYear W20233434012015 @default.
• W2023343401 countsByYear W20233434012016 @default.
• W2023343401 countsByYear W20233434012017 @default.
• W2023343401 countsByYear W20233434012018 @default.
• W2023343401 countsByYear W20233434012019 @default.
• W2023343401 countsByYear W20233434012020 @default.
• W2023343401 countsByYear W20233434012021 @default.
• W2023343401 crossrefType "journal-article" @default.
• W2023343401 hasAuthorship W2023343401A5004383514 @default.
• W2023343401 hasAuthorship W2023343401A5051491939 @default.
• W2023343401 hasAuthorship W2023343401A5082894731 @default.
• W2023343401 hasBestOaLocation W20233434011 @default.
• W2023343401 hasConcept C105702510 @default.
• W2023343401 hasConcept C123719069 @default.
• W2023343401 hasConcept C189165786 @default.
• W2023343401 hasConcept C203014093 @default.
• W2023343401 hasConcept C204232928 @default.
• W2023343401 hasConcept C28406088 @default.
• W2023343401 hasConcept C4224716 @default.
• W2023343401 hasConcept C86803240 @default.
• W2023343401 hasConcept C95444343 @default.
• W2023343401 hasConceptScore W2023343401C105702510 @default.
• W2023343401 hasConceptScore W2023343401C123719069 @default.
• W2023343401 hasConceptScore W2023343401C189165786 @default.
• W2023343401 hasConceptScore W2023343401C203014093 @default.
• W2023343401 hasConceptScore W2023343401C204232928 @default.
• W2023343401 hasConceptScore W2023343401C28406088 @default.
• W2023343401 hasConceptScore W2023343401C4224716 @default.
• W2023343401 hasConceptScore W2023343401C86803240 @default.
• W2023343401 hasConceptScore W2023343401C95444343 @default.
• W2023343401 hasIssue "1" @default.
• W2023343401 hasLocation W20233434011 @default.
• W2023343401 hasLocation W20233434012 @default.
• W2023343401 hasOpenAccess W2023343401 @default.
• W2023343401 hasPrimaryLocation W20233434011 @default.
• W2023343401 hasRelatedWork W1919167960 @default.

• next